Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA060088-03
Application #
2100713
Study Section
Virology Study Section (VR)
Project Start
1994-03-01
Project End
1997-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rutgers University
Department
Type
Schools of Medicine
DUNS #
038633251
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901
Kimmelman, Alec C; White, Eileen (2017) Autophagy and Tumor Metabolism. Cell Metab 25:1037-1043
Guo, Jessie Yanxiang; White, Eileen (2013) Autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRAS(G12D)-driven lung tumors. Autophagy 9:1636-8
Henry, Holly; Thomas, Anju; Shen, Yan et al. (2002) Regulation of the mitochondrial checkpoint in p53-mediated apoptosis confers resistance to cell death. Oncogene 21:748-60
Sullivan, Gregory F; Garcia-Welch, Adrienne; White, Eileen et al. (2002) Augmentation of apoptosis by the combination of bleomycin with trifluoperazine in the presence of mutant p53. J Exp Ther Oncol 2:19-26
Degenhardt, Kurt; Chen, Guanghua; Lindsten, Tullia et al. (2002) BAX and BAK mediate p53-independent suppression of tumorigenesis. Cancer Cell 2:193-203
Cuconati, Andrea; White, Eileen (2002) Viral homologs of BCL-2: role of apoptosis in the regulation of virus infection. Genes Dev 16:2465-78
Thomas, A; Giesler, T; White, E (2000) p53 mediates bcl-2 phosphorylation and apoptosis via activation of the Cdc42/JNK1 pathway. Oncogene 19:5259-69
Chiou, S K; White, E (1998) Inhibition of ICE-like proteases inhibits apoptosis and increases virus production during adenovirus infection. Virology 244:108-18
Thomas, A; White, E (1998) Suppression of the p300-dependent mdm2 negative-feedback loop induces the p53 apoptotic function. Genes Dev 12:1975-85
Sakamuro, D; Sabbatini, P; White, E et al. (1997) The polyproline region of p53 is required to activate apoptosis but not growth arrest. Oncogene 15:887-98

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