Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA060871-03S1
Application #
2101648
Study Section
Reproductive Endocrinology Study Section (REN)
Project Start
1993-07-15
Project End
1998-03-31
Budget Start
1995-07-01
Budget End
1998-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Physiology
Type
Schools of Dentistry
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Hamid, Tariq; Malik, Mohammed T; Millar, Robert P et al. (2008) Protein kinase A serves as a primary pathway in activation of Nur77 expression by gonadotropin-releasing hormone in the LbetaT2 mouse pituitary gonadotroph tumor cell line. Int J Oncol 33:1055-64
Mazhawidza, W; Winters, S J; Kaiser, U B et al. (2006) Identification of gene networks modulated by activin in LbetaT2 cells using DNA microarray analysis. Histol Histopathol 21:167-78
Kakar, Sham S; Malik, M Tariq; Winters, Stephen J et al. (2004) Gonadotropin-releasing hormone receptors: structure, expression, and signaling transduction. Vitam Horm 69:151-207
Okada, Yohei; Murota-Kawano, Akiko; Kakar, Sham S et al. (2003) Evidence that gonadotropin-releasing hormone (GnRH) II stimulates luteinizing hormone and follicle-stimulating hormone secretion from monkey pituitary cultures by activating the GnRH I receptor. Biol Reprod 69:1356-61
Kakar, S S (1999) Molecular cloning, genomic organization, and identification of the promoter for the human pituitary tumor transforming gene (PTTG). Gene 240:317-24
Kakar, S S; Jennes, L (1999) Molecular cloning and characterization of the tumor transforming gene (TUTR1): a novel gene in human tumorigenesis. Cytogenet Cell Genet 84:211-6
Kakar, S S (1998) Inhibition of growth and proliferation of EcRG293 cell line expressing high-affinity gonadotropin-releasing hormone (GnRH) receptor under the control of an inducible promoter by GnRH agonist (D-Lys6)GnRH and antagonist (Antide). Cancer Res 58:4558-60
Kakar, S S (1998) Assignment of the human tumor transforming gene TUTR1 to chromosome band 5q35.1 by fluorescence in situ hybridization. Cytogenet Cell Genet 83:93-5
Kakar, S S; Nath, S; Bunn, J et al. (1997) The inhibition of growth and down-regulation of gonadotropin releasing hormone (GnRH) receptor in alphaT3-1 cells by GnRH agonist. Anticancer Drugs 8:369-75
Kakar, S S (1997) Molecular structure of the human gonadotropin-releasing hormone receptor gene. Eur J Endocrinol 137:183-92

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