|
Francis, Jonathan W; Figueiredo, Dayse; vanderSpek, Johanna C et al. (2004) A survival motor neuron:tetanus toxin fragment C fusion protein for the targeted delivery of SMN protein to neurons. Brain Res 995:84-96
|
|
Ratts, Ryan; Zeng, Huiyan; Berg, Eric A et al. (2003) The cytosolic entry of diphtheria toxin catalytic domain requires a host cell cytosolic translocation factor complex. J Cell Biol 160:1139-50
|
|
Hu, H Y; Huynh, P D; Murphy, J R et al. (1998) The effects of helix breaking mutations in the diphtheria toxin transmembrane domain helix layers of the fusion toxin DAB389IL-2. Protein Eng 11:811-7
|
|
vanderSpek, J C; Sutherland, J A; Zeng, H et al. (1997) Inhibition of protein synthesis in small cell lung cancer cells induced by the diphtheria toxin-related fusion protein DAB389 GRP. Cancer Res 57:290-4
|
|
Fisher, C E; Sutherland, J A; Krause, J E et al. (1996) Genetic construction and properties of a diphtheria toxin-related substance P fusion protein: in vitro destruction of cells bearing substance P receptors. Proc Natl Acad Sci U S A 93:7341-5
|
|
vanderSpek, J C; Sutherland, J A; Ratnarathorn, M et al. (1996) DAB389 interleukin-2 receptor binding domain mutations. Cytotoxic probes for studies of ligand-receptor interactions. J Biol Chem 271:12145-9
|
|
Murphy, J R; vanderSpek, J C (1995) Targeting diphtheria toxin to growth factor receptors. Semin Cancer Biol 6:259-67
|
|
vanderSpek, J; Cassidy, D; Genbauffe, F et al. (1994) An intact transmembrane helix 9 is essential for the efficient delivery of the diphtheria toxin catalytic domain to the cytosol of target cells. J Biol Chem 269:21455-9
|
|
vanderSpek, J C; Howland, K; Friedman, T et al. (1994) Maintenance of the hydrophobic face of the diphtheria toxin amphipathic transmembrane helix 1 is essential for the efficient delivery of the catalytic domain to the cytosol of target cells. Protein Eng 7:985-9
|
