Fiber, Short Chain Fatty Acids and Colon Cancer

Lupton, Joanne R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA061750-03
• Application #: 2102516
• Study Section: Special Emphasis Panel (SRC (70))
• Project Start: 1994-08-01
• Project End: 1999-05-31
• Budget Start: 1996-06-01
• Budget End: 1997-05-31
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: Texas Agrilife Research
• Department: Veterinary Sciences
• Type: Schools of Earth Sciences/Natur
• DUNS #: 110521739
• City: College Station
• State: TX
• Country: United States
• Zip Code: 77843

Publications

Hong, Mee Young; Turner, Nancy D; Murphy, Mary E et al. (2015) In vivo regulation of colonic cell proliferation, differentiation, apoptosis, and P27Kip1 by dietary fish oil and butyrate in rats. Cancer Prev Res (Phila) 8:1076-83

Cho, Youngmi; Turner, Nancy D; Davidson, Laurie A et al. (2014) Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation. Exp Biol Med (Maywood) 239:302-10

Cho, Youngmi; Turner, Nancy D; Davidson, Laurie A et al. (2012) A chemoprotective fish oil/pectin diet enhances apoptosis via Bcl-2 promoter methylation in rat azoxymethane-induced carcinomas. Exp Biol Med (Maywood) 237:1387-93

Cho, Youngmi; Kim, Hyemee; Turner, Nancy D et al. (2011) A chemoprotective fish oil- and pectin-containing diet temporally alters gene expression profiles in exfoliated rat colonocytes throughout oncogenesis. J Nutr 141:1029-35

Vanamala, J; Glagolenko, A; Yang, P et al. (2008) Dietary fish oil and pectin enhance colonocyte apoptosis in part through suppression of PPARdelta/PGE2 and elevation of PGE3. Carcinogenesis 29:790-6

Apanasovich, Tatiyana V; Ruppert, David; Lupton, Joanne R et al. (2008) Aberrant crypt foci and semiparametric modeling of correlated binary data. Biometrics 64:490-500

Crim, Kristy Covert; Sanders, Lisa M; Hong, Mee Young et al. (2008) Upregulation of p21Waf1/Cip1 expression in vivo by butyrate administration can be chemoprotective or chemopromotive depending on the lipid component of the diet. Carcinogenesis 29:1415-20

Baladandayuthapani, Veerabhadran; Mallick, Bani K; Young Hong, Mee et al. (2008) Bayesian hierarchical spatially correlated functional data analysis with application to colon carcinogenesis. Biometrics 64:64-73

Hong, Mee Young; Turner, Nancy D; Carroll, Raymond J et al. (2005) Differential response to DNA damage may explain different cancer susceptibility between small and large intestine. Exp Biol Med (Maywood) 230:464-71

Hong, Mee Young; Bancroft, Laura K; Turner, Nancy D et al. (2005) Fish oil decreases oxidative DNA damage by enhancing apoptosis in rat colon. Nutr Cancer 52:166-75