Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA062014-03
Application #
2102956
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1994-07-22
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Roswell Park Cancer Institute Corp
Department
Type
DUNS #
City
Buffalo
State
NY
Country
United States
Zip Code
14263
Winston, J S; Asch, H L; Zhang, P J et al. (2001) Downregulation of gelsolin correlates with the progression to breast carcinoma. Breast Cancer Res Treat 65:11-21
VanHouten, J N; Asch, H L; Asch, B B (2001) Cloning and characterization of ectopically expressed transcripts for the actin-binding protein MIPP in mouse mammary carcinomas. Oncogene 20:5366-72
Crowley, M R; Head, K L; Kwiatkowski, D J et al. (2000) The mouse mammary gland requires the actin-binding protein gelsolin for proper ductal morphogenesis. Dev Biol 225:407-23
Mielnicki, L M; Ying, A M; Head, K L et al. (1999) Epigenetic regulation of gelsolin expression in human breast cancer cells. Exp Cell Res 249:161-76
Dong, Y; Asch, H L; Medina, D et al. (1999) Concurrent deregulation of gelsolin and cyclin D1 in the majority of human and rodent breast cancers. Int J Cancer 81:930-8
Asch, H L; Winston, J S; Edge, S B et al. (1999) Down-regulation of gelsolin expression in human breast ductal carcinoma in situ with and without invasion. Breast Cancer Res Treat 55:179-88
Asch, B B (1996) Tumor viruses and endogenous retrotransposons in mammary tumorigenesis. J Mammary Gland Biol Neoplasia 1:49-60
Asch, H L; Eliacin, E; Fanning, T G et al. (1996) Comparative expression of the LINE-1 p40 protein in human breast carcinomas and normal breast tissues. Oncol Res 8:239-47
Asch, H L; Head, K; Dong, Y et al. (1996) Widespread loss of gelsolin in breast cancers of humans, mice, and rats. Cancer Res 56:4841-5
Natoli, F; Crowley, M R; Asch, H L et al. (1996) Mutations involving the endogenous ecotropic murine leukemia virus in primary mammary carcinomas of BALB/c mice. Cancer Lett 99:121-7