Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA062550-01A3
Application #
2103865
Study Section
Experimental Immunology Study Section (EI)
Project Start
1996-02-01
Project End
1998-12-31
Budget Start
1996-02-01
Budget End
1996-12-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Alabama Birmingham
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Safavy, Ahmad; Smith Jr, Dale C; Bazooband, Alireza et al. (2002) Synthesis of the first diethylenetriaminepentahydroxamic acid (DTPH) bifunctional chelating agent. Bioconjug Chem 13:327-32
Safavy, Ahmad; Smith Jr, Dale C; Bazooband, Alireza et al. (2002) De novo synthesis of a new diethylenetriaminepentaacetic acid (DTPA) bifunctional chelating agent. Bioconjug Chem 13:317-26
Buchsbaum, D J; Curiel, D T (2001) Gene therapy for the treatment of cancer. Cancer Biother Radiopharm 16:275-88
Buchsbaum, D J (2000) Experimental radioimmunotherapy. Semin Radiat Oncol 10:156-67
Safavy, A; Khazaeli, M B; Kirk, M et al. (1999) Further studies on the protein conjugation of hydroxamic acid bifunctional chelating agents: group-specific conjugation at two different loci. Bioconjug Chem 10:18-23
Safavy, A; Khazaeli, M B; Safavy, K et al. (1999) Biodistribution study of 188Re-labeled trisuccin-HuCC49 and trisuccin-HuCC49deltaCh2 conjugates in athymic nude mice bearing intraperitoneal colon cancer xenografts. Clin Cancer Res 5:2994s-3000s
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Safavy, A; Sanders, A; Qin, H et al. (1997) Conjugation of unprotected trisuccin, N-[tris[2-[(N-hydroxyamino)carbonyl]ethyl]methyl]succinamic acid, to monoclonal antibody CC49 by an improved active ester protocol. Bioconjug Chem 8:766-71
Safavy, A; Khazaeli, M B; Qin, H et al. (1997) Synthesis of bombesin analogues for radiolabeling with rhenium-188. Cancer 80:2354-9
Buchsbaum, D J (1997) Experimental tumor targeting with radiolabeled ligands. Cancer 80:2371-7