|
Song, Lin; Bevins, Robert; Anderson, Bradley D (2006) Kinetics and mechanisms of activation of alpha-amino acid ester prodrugs of camptothecins. J Med Chem 49:4344-55
|
|
Lopez-Barcons, Lluis A; Zhang, Junhong; Siriwitayawan, Gunching et al. (2004) The novel highly lipophilic topoisomerase I inhibitor DB67 is effective in the treatment of liver metastases of murine CT-26 colon carcinoma. Neoplasia 6:457-67
|
|
Liu, Xinli; Zhang, Junhong; Song, Lin et al. (2004) Degradation of camptothecin-20(S)-glycinate ester prodrug under physiological conditions. J Pharm Biomed Anal 35:1113-25
|
|
Du, Wu; Curran, Dennis P; Bevins, Robert L et al. (2002) Synthesis and evaluation of a novel E-ring modified alpha-hydroxy keto ether analogue of camptothecin. Bioorg Med Chem 10:103-10
|
|
Liu, Xinli; Lynn, Bert C; Zhang, Junhong et al. (2002) A versatile prodrug approach for liposomal core-loading of water-insoluble camptothecin anticancer drugs. J Am Chem Soc 124:7650-1
|
|
Bom, D; Curran, D P; Zhang, J et al. (2001) The highly lipophilic DNA topoisomerase I inhibitor DB-67 displays elevated lactone levels in human blood and potent anticancer activity. J Control Release 74:325-33
|
|
Bom, D; Curran, D P; Kruszewski, S et al. (2000) The novel silatecan 7-tert-butyldimethylsilyl-10-hydroxycamptothecin displays high lipophilicity, improved human blood stability, and potent anticancer activity. J Med Chem 43:3970-80
|
|
Bom, D; Curran, D P; Chavan, A J et al. (1999) Novel A,B,E-ring-modified camptothecins displaying high lipophilicity and markedly improved human blood stabilities. J Med Chem 42:3018-22
|
|
Pollack, I F; Erff, M; Bom, D et al. (1999) Potent topoisomerase I inhibition by novel silatecans eliminates glioma proliferation in vitro and in vivo. Cancer Res 59:4898-905
|
|
Shenderova, A; Burke, T G; Schwendeman, S P (1999) The acidic microclimate in poly(lactide-co-glycolide) microspheres stabilizes camptothecins. Pharm Res 16:241-8
|
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