Mechanisms for Oxidative Stress-Induced Apoptosis

Held, Kathryn Dale

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 2R01CA063997-04
• Application #: 6130422
• Study Section: Special Emphasis Panel (ZRG1-MEP (02))
• Program Officer: Yang, Shen K
• Project Start: 1997-04-10
• Project End: 2003-03-31
• Budget Start: 2000-04-01
• Budget End: 2001-03-31
• Support Year: 4
• Fiscal Year: 2000
• Total Cost: $293,401

Institution

• Name: Massachusetts General Hospital
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02199

Publications

Biaglow, J E; Donahue, J; Tuttle, S et al. (2000) A method for measuring disulfide reduction by cultured mammalian cells: relative contributions of glutathione-dependent and glutathione-independent mechanisms. Anal Biochem 281:77-86

Tartier, L; McCarey, Y L; Biaglow, J E et al. (2000) Apoptosis induced by dithiothreitol in HL-60 cells shows early activation of caspase 3 and is independent of mitochondria. Cell Death Differ 7:1002-10

Manevich, Y; Held, K D; Biaglow, J E (1997) Coumarin-3-carboxylic acid as a detector for hydroxyl radicals generated chemically and by gamma radiation. Radiat Res 148:580-91