Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA064654-03
Application #
2107266
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1994-07-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Pharmacology
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Lui, V W; He, Y; Huang, L (2001) Specific down-regulation of HER-2/neu mediated by a chimeric U6 hammerhead ribozyme results in growth inhibition of human ovarian carcinoma. Mol Ther 3:169-77
Whitmore, M; Li, S; Huang, L (1999) LPD lipopolyplex initiates a potent cytokine response and inhibits tumor growth. Gene Ther 6:1867-75
Li, S; Tseng, W C; Stolz, D B et al. (1999) Dynamic changes in the characteristics of cationic lipidic vectors after exposure to mouse serum: implications for intravenous lipofection. Gene Ther 6:585-94
Zou, L L; Huang, L; Hayes, R L et al. (1999) Liposome-mediated NGF gene transfection following neuronal injury: potential therapeutic applications. Gene Ther 6:994-1005
Li, S; Wu, S P; Whitmore, M et al. (1999) Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors. Am J Physiol 276:L796-804
Brisson, M; He, Y; Li, S et al. (1999) A novel T7 RNA polymerase autogene for efficient cytoplasmic expression of target genes. Gene Ther 6:263-70
Li, S; Rizzo, M A; Bhattacharya, S et al. (1998) Characterization of cationic lipid-protamine-DNA (LPD) complexes for intravenous gene delivery. Gene Ther 5:930-7
Yang, J P; Huang, L (1998) Time-dependent maturation of cationic liposome-DNA complex for serum resistance. Gene Ther 5:380-7
He, Y K; Lui, V W; Baar, J et al. (1998) Potentiation of E7 antisense RNA-induced antitumor immunity by co-delivery of IL-12 gene in HPV16 DNA-positive mouse tumor. Gene Ther 5:1462-71
He, Y; Zeng, Q; Drenning, S D et al. (1998) Inhibition of human squamous cell carcinoma growth in vivo by epidermal growth factor receptor antisense RNA transcribed from the U6 promoter. J Natl Cancer Inst 90:1080-7

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