Cytokine and Growth Factor Pathways in Kaposis Sarcoma

Nel, Andre Elias

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Cancer Institute (NCI)
• Type: Research Project (R01)
• Project #: 5R01CA065329-03
• Application #: 2108274
• Study Section: AIDS and Related Research Study Section 1 (ARRA)
• Project Start: 1994-07-01
• Project End: 1999-04-30
• Budget Start: 1996-05-01
• Budget End: 1997-04-30
• Support Year: 3
• Fiscal Year: 1996

Institution

• Name: University of California Los Angeles
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 119132785
• City: Los Angeles
• State: CA
• Country: United States
• Zip Code: 90095

Publications

Barillari, G; Sgadari, C; Palladino, C et al. (1999) Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin. J Immunol 163:1929-35

Faris, M; Ensoli, B; Kokot, N et al. (1998) Inflammatory cytokines induce the expression of basic fibroblast growth factor (bFGF) isoforms required for the growth of Kaposi's sarcoma and endothelial cells through the activation of AP-1 response elements in the bFGF promoter. AIDS 12:19-27

Faris, M; Ensoli, B; Stahl, N et al. (1996) Differential activation of the extracellular signal-regulated kinase, Jun kinase and Janus kinase-Stat pathways by oncostatin M and basic fibroblast growth factor in AIDS-derived Kaposi's sarcoma cells. AIDS 10:369-78