Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA065769-02
Application #
2108893
Study Section
Experimental Therapeutics Subcommittee 1 (ET)
Project Start
1995-08-21
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Kim, Y G; Bi, W; Feliciano, E S et al. (2000) Ganciclovir-mediated cell killing and bystander effect is enhanced in cells with two copies of the herpes simplex virus thymidine kinase gene. Cancer Gene Ther 7:240-6
Wang, X; Gleich, L; Pavelic, Z P et al. (1999) Cervical metastases of head and neck squamous cell carcinoma correlate with loss of heterozygosity on chromosome 16q. Int J Oncol 14:557-61
Saavedra, H I; Fukasawa, K; Conn, C W et al. (1999) MAPK mediates RAS-induced chromosome instability. J Biol Chem 274:38083-90
Gleich, L L; Gluckman, J L; Armstrong, S et al. (1998) Alloantigen gene therapy for squamous cell carcinoma of the head and neck: results of a phase-1 trial. Arch Otolaryngol Head Neck Surg 124:1097-104
Bi, W; Stambrook, P J (1998) Site-directed mutagenesis by combined chain reaction. Anal Biochem 256:137-40
Bi, W; Stambrook, P J (1998) Detection of known mutation by proof-reading PCR. Nucleic Acids Res 26:3073-5
Bi, W; Stambrook, P J (1997) CCR: a rapid and simple approach for mutation detection. Nucleic Acids Res 25:2949-51
Bi, W; Kim, Y G; Feliciano, E S et al. (1997) An HSVtk-mediated local and distant antitumor bystander effect in tumors of head and neck origin in athymic mice. Cancer Gene Ther 4:246-52
Wilson, K M; Stambrook, P J; Bi, W L et al. (1996) HSV-tk gene therapy in head and neck squamous cell carcinoma. Enhancement by the local and distant bystander effect. Arch Otolaryngol Head Neck Surg 122:746-9