Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA066271-03
Application #
2109596
Study Section
Special Emphasis Panel (SRC (70))
Project Start
1994-05-13
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Lee, S W; Reimer, C L; Fang, L et al. (2000) Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression. Mol Cell Biol 20:1723-32
Fang, L; Igarashi, M; Leung, J et al. (1999) p21Waf1/Cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53. Oncogene 18:2789-97
Lee, S W; Reimer, C L; Campbell, D B et al. (1998) H-cadherin expression inhibits in vitro invasiveness and tumor formation in vivo. Carcinogenesis 19:1157-9
Lee, S W; Reimer, C L; Oh, P et al. (1998) Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells. Oncogene 16:1391-7
Kurdistani, S K; Arizti, P; Reimer, C L et al. (1998) Inhibition of tumor cell growth by RTP/rit42 and its responsiveness to p53 and DNA damage. Cancer Res 58:4439-44
Sugrue, M M; Shin, D Y; Lee, S W et al. (1997) Wild-type p53 triggers a rapid senescence program in human tumor cells lacking functional p53. Proc Natl Acad Sci U S A 94:9648-53
Lee, S W; Fukunaga, N; Rigney, D R et al. (1997) Downregulation of DNA topoisomerase I in old versus young human diploid fibroblasts. Mutat Res 373:179-84
Kocher, O; Cheresh, P; Lee, S W (1996) Identification and partial characterization of a novel membrane-associated protein (MAP17) up-regulated in human carcinomas and modulating cell replication and tumor growth. Am J Pathol 149:493-500
Lee, S W (1996) H-cadherin, a novel cadherin with growth inhibitory functions and diminished expression in human breast cancer. Nat Med 2:776-82
Kocher, O; Cheresh, P; Brown, L F et al. (1995) Identification of a novel gene, selectively up-regulated in human carcinomas, using the differential display technique. Clin Cancer Res 1:1209-15