Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA066671-01A1
Application #
2110111
Study Section
Biochemistry Study Section (BIO)
Project Start
1996-02-12
Project End
2000-11-30
Budget Start
1996-02-12
Budget End
1996-11-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wistar Institute
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Trebak, M; Begg, G E; Chong, J M et al. (2001) Oligomeric state of the colon carcinoma-associated glycoprotein GA733-2 (Ep-CAM/EGP40) and its role in GA733-mediated homotypic cell-cell adhesion. J Biol Chem 276:2299-309
Zuo, X; Speicher, D W (2000) Quantitative evaluation of protein recoveries in two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 21:3035-47
Lechner, M S; Begg, G E; Speicher, D W et al. (2000) Molecular determinants for targeting heterochromatin protein 1-mediated gene silencing: direct chromoshadow domain-KAP-1 corepressor interaction is essential. Mol Cell Biol 20:6449-65
Peng, H; Begg, G E; Schultz, D C et al. (2000) Reconstitution of the KRAB-KAP-1 repressor complex: a model system for defining the molecular anatomy of RING-B box-coiled-coil domain-mediated protein-protein interactions. J Mol Biol 295:1139-62
Trebak, M; Chong, J M; Herlyn, D et al. (1999) Efficient laboratory-scale production of monoclonal antibodies using membrane-based high-density cell culture technology. J Immunol Methods 230:59-70
Basak, S; Speicher, D; Eck, S et al. (1998) Colorectal carcinoma invasion inhibition by CO17-1A/GA733 antigen and its murine homologue. J Natl Cancer Inst 90:691-7
Sebti, S; Hamilton, A D (1997) Inhibitors of prenyl transferases. Curr Opin Oncol 9:557-61
Sebti, S M; Hamilton, A D (1997) Inhibition of Ras prenylation: a novel approach to cancer chemotherapy. Pharmacol Ther 74:103-14
Shih, I M; Speicher, D; Hsu, M Y et al. (1997) Melanoma cell-cell interactions are mediated through heterophilic Mel-CAM/ligand adhesion. Cancer Res 57:3835-40