Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA067173-02
Application #
2110778
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1995-06-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Sun, H; Gutierrez, P; Jackson, M J et al. (2000) Essential role of nitric oxide and interferon-gamma for tumor immunotherapy with interleukin-10. J Immunother 23:208-14
Sun, H; Jackson, M J; Kundu, N et al. (1999) Interleukin-10 gene transfer activates interferon-gamma and the interferon-gamma-inducible genes Gbp-1/Mag-1 and Mig-1 in mammary tumors. Int J Cancer 80:624-9
Kundu, N; Dorsey, R; Jackson, M J et al. (1998) Interleukin-10 gene transfer inhibits murine mammary tumors and elevates nitric oxide. Int J Cancer 76:713-9
Book, A A; Fielding, K E; Kundu, N et al. (1998) IL-10 gene transfer to intracranial 9L glioma: tumor inhibition and cooperation with IL-2. J Neuroimmunol 92:50-9
Kundu, N; Fulton, A M (1997) Interleukin-10 inhibits tumor metastasis, downregulates MHC class I, and enhances NK lysis. Cell Immunol 180:55-61
Kundu, N; Beaty, T L; Jackson, M J et al. (1996) Antimetastatic and antitumor activities of interleukin 10 in a murine model of breast cancer. J Natl Cancer Inst 88:536-41