Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA069769-02
Application #
2668032
Study Section
Diagnostic Radiology Study Section (RNM)
Program Officer
Menkens, Anne E
Project Start
1997-05-01
Project End
2000-04-30
Budget Start
1998-05-11
Budget End
1999-04-30
Support Year
2
Fiscal Year
1998
Total Cost
Indirect Cost
Name
Sloan-Kettering Institute for Cancer Research
Department
Type
DUNS #
064931884
City
New York
State
NY
Country
United States
Zip Code
10065
Qiao, J; Doubrovin, M; Sauter, B V et al. (2002) Tumor-specific transcriptional targeting of suicide gene therapy. Gene Ther 9:168-75
Bennett, J J; Tjuvajev, J; Johnson, P et al. (2001) Positron emission tomography imaging for herpes virus infection: Implications for oncolytic viral treatments of cancer. Nat Med 7:859-63
Doubrovin, M; Ponomarev, V; Beresten, T et al. (2001) Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo. Proc Natl Acad Sci U S A 98:9300-5
Gambhir, S S; Herschman, H R; Cherry, S R et al. (2000) Imaging transgene expression with radionuclide imaging technologies. Neoplasia 2:118-38
Sadelain, M; Blasberg, R G (1999) Imaging transgene expression for gene therapy. J Clin Pharmacol Suppl:34S-39S
Tjuvajev, J G; Joshi, A; Callegari, J et al. (1999) A general approach to the non-invasive imaging of transgenes using cis-linked herpes simplex virus thymidine kinase. Neoplasia 1:315-20
Oku, T; Tjuvajev, J G; Miyagawa, T et al. (1998) Tumor growth modulation by sense and antisense vascular endothelial growth factor gene expression: effects on angiogenesis, vascular permeability, blood volume, blood flow, fluorodeoxyglucose uptake, and proliferation of human melanoma intracerebral xenog Cancer Res 58:4185-92
Tjuvajev, J G; Avril, N; Oku, T et al. (1998) Imaging herpes virus thymidine kinase gene transfer and expression by positron emission tomography. Cancer Res 58:4333-41