Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA070149-01
Application #
2114096
Study Section
Experimental Immunology Study Section (EI)
Project Start
1996-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Pathology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Bagheri, Nayer; Pepple, Douglas A; Hassan, Medhat O et al. (2005) Development of immune-complex glomerulonephritis in athymic mice: T cells are not required for the genesis of glomerular injury. Lab Invest 85:354-63
Johnsen, A K; France, J; Nagy, N et al. (2001) Systemic deficits in transporter for antigen presentation (TAP)-1 or proteasome subunit LMP2 have little or no effect on tumor incidence. Int J Cancer 91:366-72
Ramachandra, L; Song, R; Harding, C V (1999) Phagosomes are fully competent antigen-processing organelles that mediate the formation of peptide:class II MHC complexes. J Immunol 162:3263-72
Song, R; Porgador, A; Harding, C V (1999) Peptide-receptive class I major histocompatibility complex molecules on TAP-deficient and wild-type cells and their roles in the processing of exogenous antigens. Immunology 97:316-24
Johnsen, A K; Templeton, D J; Sy, M et al. (1999) Deficiency of transporter for antigen presentation (TAP) in tumor cells allows evasion of immune surveillance and increases tumorigenesis. J Immunol 163:4224-31
Ramachandra, L; Chu, R S; Askew, D et al. (1999) Phagocytic antigen processing and effects of microbial products on antigen processing and T-cell responses. Immunol Rev 168:217-39
De Silva, A D; Boesteanu, A; Song, R et al. (1999) Thermolabile H-2Kb molecules expressed by transporter associated with antigen processing-deficient RMA-S cells are occupied by low-affinity peptides. J Immunol 163:4413-20
Matousek, M P; Nedrud, J G; Cieplak Jr, W et al. (1998) Inhibition of class II major histocompatibility complex antigen processing by Escherichia coli heat-labile enterotoxin requires an enzymatically active A subunit. Infect Immun 66:3480-4
Johnsen, A; France, J; Sy, M S et al. (1998) Down-regulation of the transporter for antigen presentation, proteasome subunits, and class I major histocompatibility complex in tumor cell lines. Cancer Res 58:3660-7
Ramachandra, L; Sramkoski, R M; Canaday, D H et al. (1998) Flow analysis of MHC molecules and other membrane proteins in isolated phagosomes. J Immunol Methods 213:53-71

Showing the most recent 10 out of 13 publications