Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA070817-07
Application #
6628319
Study Section
Special Emphasis Panel (ZRG1-SOH (02))
Program Officer
Hartmuller, Virginia W
Project Start
1996-08-01
Project End
2006-05-31
Budget Start
2003-06-01
Budget End
2004-05-31
Support Year
7
Fiscal Year
2003
Total Cost
$273,360
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
030811269
City
Boston
State
MA
Country
United States
Zip Code
02115
Schernhammer, Eva S; Giovannucci, Edward; Kawasaki, Takako et al. (2010) Dietary folate, alcohol and B vitamins in relation to LINE-1 hypomethylation in colon cancer. Gut 59:794-9
Hazra, Aditi; Fuchs, Charles S; Kawasaki, Takako et al. (2010) Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer. Cancer Causes Control 21:331-45
Hazra, Aditi; Kraft, Peter; Lazarus, Ross et al. (2009) Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway. Hum Mol Genet 18:4677-87
Hazra, Aditi; Fuchs, Charles S; Chan, Andrew T et al. (2008) Association of the TCF7L2 polymorphism with colorectal cancer and adenoma risk. Cancer Causes Control 19:975-80
Schernhammer, Eva S; Ogino, Shuji; Fuchs, Charles S (2008) Folate and vitamin B6 intake and risk of colon cancer in relation to p53 expression. Gastroenterology 135:770-80
Hazra, Aditi; Chanock, Stephen; Giovannucci, Edward et al. (2008) Large-scale evaluation of genetic variants in candidate genes for colorectal cancer risk in the Nurses'Health Study and the Health Professionals'Follow-up Study. Cancer Epidemiol Biomarkers Prev 17:311-9
Grodstein, Francine; Manson, JoAnn E; Stampfer, Meir J et al. (2008) Postmenopausal hormone therapy and stroke: role of time since menopause and age at initiation of hormone therapy. Arch Intern Med 168:861-6
Schernhammer, Eva S; Giovannuccci, Edward; Fuchs, Charles S et al. (2008) A prospective study of dietary folate and vitamin B and colon cancer according to microsatellite instability and KRAS mutational status. Cancer Epidemiol Biomarkers Prev 17:2895-8
Hazra, Aditi; Kraft, Peter; Selhub, Jacob et al. (2008) Common variants of FUT2 are associated with plasma vitamin B12 levels. Nat Genet 40:1160-2
Schernhammer, Eva; Wolpin, Brian; Rifai, Nader et al. (2007) Plasma folate, vitamin B6, vitamin B12, and homocysteine and pancreatic cancer risk in four large cohorts. Cancer Res 67:5553-60

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