Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA071426-01
Application #
2115055
Study Section
Chemical Pathology Study Section (CPA)
Project Start
1996-09-01
Project End
2000-06-30
Budget Start
1996-09-01
Budget End
1997-06-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Institute for Cancer Research
Department
Type
DUNS #
872612445
City
Philadelphia
State
PA
Country
United States
Zip Code
19111
Pimkin, Maxim; Caretti, Elena; Canutescu, Adrian et al. (2007) Recombinant nucleases CEL I from celery and SP I from spinach for mutation detection. BMC Biotechnol 7:29
Pimkin, Maxim; Miller, C Glenn; Blakesley, Lauryn et al. (2006) Characterization of a periplasmic S1-like nuclease coded by the Mesorhizobium loti symbiosis island. Biochem Biophys Res Commun 343:77-84
Yeung, Anthony T; Hattangadi, Deepali; Blakesley, Lauryn et al. (2005) Enzymatic mutation detection technologies. Biotechniques 38:749-58
Colbert, T; Till, B J; Tompa, R et al. (2001) High-throughput screening for induced point mutations. Plant Physiol 126:480-4
Kulinski, J; Besack, D; Oleykowski, C A et al. (2000) CEL I enzymatic mutation detection assay. Biotechniques 29:44-6, 48
Petronzelli, F; Riccio, A; Markham, G D et al. (2000) Biphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylase. J Biol Chem 275:32422-9
Yang, B; Wen, X; Kodali, N S et al. (2000) Purification, cloning, and characterization of the CEL I nuclease. Biochemistry 39:3533-41
Jaffe, E K; Volin, M; Bronson-Mullins, C R et al. (2000) An artificial gene for human porphobilinogen synthase allows comparison of an allelic variation implicated in susceptibility to lead poisoning. J Biol Chem 275:2619-26
Petronzelli, F; Riccio, A; Markham, G D et al. (2000) Investigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domain. J Cell Physiol 185:473-80
Oleykowski, C A; Bronson Mullins, C R; Chang, D W et al. (1999) Incision at nucleotide insertions/deletions and base pair mismatches by the SP nuclease of spinach. Biochemistry 38:2200-5

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