Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
1R01CA071590-01
Application #
2115174
Study Section
Pathology B Study Section (PTHB)
Project Start
1996-08-10
Project End
2001-05-31
Budget Start
1996-08-10
Budget End
1997-05-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Santa Cruz
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Santa Cruz
State
CA
Country
United States
Zip Code
95064
Thordarson, Gudmundur; Slusher, Nicole; Leong, Harriet et al. (2004) Insulin-like growth factor (IGF)-I obliterates the pregnancy-associated protection against mammary carcinogenesis in rats: evidence that IGF-I enhances cancer progression through estrogen receptor-alpha activation via the mitogen-activated protein kinase Breast Cancer Res 6:R423-36
Talamantes, F; Ortiz, R (2002) Structure and regulation of expression of the mouse GH receptor. J Endocrinol 175:55-9
Thordarson, G; Lee, A V; McCarty, M et al. (2001) Growth and characterization of N-methyl-N-nitrosourea-induced mammary tumors in intact and ovariectomized rats. Carcinogenesis 22:2039-47
Camarillo, I G; Thordarson, G; Moffat, J G et al. (2001) Prolactin receptor expression in the epithelia and stroma of the rat mammary gland. J Endocrinol 171:85-95
Thordarson, G; Van Horn, K; Guzman, R C et al. (2001) Parous rats regain high susceptibility to chemically induced mammary cancer after treatment with various mammotropic hormones. Carcinogenesis 22:1027-33
Rajkumar, L; Guzman, R C; Yang, J et al. (2001) Short-term exposure to pregnancy levels of estrogen prevents mammary carcinogenesis. Proc Natl Acad Sci U S A 98:11755-9
Moffat, J G; Dao, H; Talamantes, F (2000) Alternative 5'-untranslated regions of mouse GH receptor/binding protein messenger RNA are derived from sequences adjacent to the major L2 promoter. J Endocrinol 167:145-52
Shyamala, G; Louie, S G; Camarillo, I G et al. (1999) The progesterone receptor and its isoforms in mammary development. Mol Genet Metab 68:182-90
Contreras, B; Talamantes, F (1999) Growth hormone (GH) and 17beta-estradiol regulation of the expression of mouse GH receptor and GH-binding protein in cultured mouse hepatocytes. Endocrinology 140:4725-31
Moffat, J G; Edens, A; Talamantes, F (1999) Structure and expression of the mouse growth hormone receptor/growth hormone binding protein gene. J Mol Endocrinol 23:33-44

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