) African-American women have disproportionately high cancer incidence and mortality rates. Of all major United States ethnic/gender groups, African-American women are, on the average, the most likely to be overweight and the least physically active. Mounting evidence links these factors, along with diet, to cancer etiology. Yet few cancer prevention studies have investigated the determinants of these risk factors or developed interventions culturally targeted to address them. The study proposed here, African-American Women Fight Cancer with Fitness (FCF), examines the effectiveness of a randomized, community-based, nutrition-exercise intervention trial aimed at middle income African-American women representing a broad range of ages. Participants will be randomly assigned to eight weekly interactive group sessions providing culturally tailored high-complex carbohydrate/low-fat nutrition and balanced (strength training, aerobic activity, and flexibility enhancement) exercise instruction (intervention) or eight women s/African-American health issues seminars focused on cancer screening promotion (attention control). Outcome measures of body mass index (BMI), waist-to-hip ratio (WHR), and percent body fat by bioelectrical impedance analysis (BIA) will be assessed at 2, 6, and 12 months of follow-up. This research will test the hypothesis that the FCF intervention can favorably influence body composition in African-American women. Secondary analyses are expected to show that any significant outcomes are highly correlated with changes in dietary behavior and physical activity patterns, and correlated with social support.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA073512-02
Application #
2517777
Study Section
Special Emphasis Panel (SRC (C1))
Project Start
1996-09-30
Project End
1999-08-30
Budget Start
1997-08-31
Budget End
1998-08-30
Support Year
2
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Public Health
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
McCarthy, William J; Yancey, Antronette K; Harrison, Gail G et al. (2007) Fighting cancer with fitness: dietary outcomes of a randomized, controlled lifestyle change intervention in healthy African-American women. Prev Med 44:246-53
Yancey, Antronette K; McCarthy, William J; Harrison, Gail G et al. (2006) Challenges in improving fitness: results of a community-based, randomized, controlled lifestyle change intervention. J Womens Health (Larchmt) 15:412-29
Yancey, A K; Miles, O L; McCarthy, W J et al. (2001) Differential response to targeted recruitment strategies to fitness promotion research by African-American women of varying body mass index. Ethn Dis 11:115-23
Siegel, J M; Yancey, A K; McCarthy, W J (2000) Overweight and depressive symptoms among African-American women. Prev Med 31:232-40
Yancey, A; McCarthy, W J; Leslie, J (1998) Recruiting African-American women to community-based health promotion research. Am J Health Promot 12:335-8