Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA075218-02
Application #
6124562
Study Section
Hematology Subcommittee 2 (HEM)
Program Officer
Mufson, R Allan
Project Start
1998-12-07
Project End
2002-11-30
Budget Start
1999-12-01
Budget End
2000-11-30
Support Year
2
Fiscal Year
2000
Total Cost
$203,773
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
004413456
City
Nashville
State
TN
Country
United States
Zip Code
37212
Zhao, Runxiang; Fu, Xueqi; Teng, Lirong et al. (2003) Blocking the function of tyrosine phosphatase SHP-2 by targeting its Src homology 2 domains. J Biol Chem 278:42893-8
Wu, Chengyu; Guan, Qin; Wang, Yingjian et al. (2003) SHP-1 suppresses cancer cell growth by promoting degradation of JAK kinases. J Cell Biochem 90:1026-37
Zhao, Runxiang; Zhao, Zhizhuang Joe (2003) Identification of a variant form of PZR lacking immunoreceptor tyrosine-based inhibitory motifs. Biochem Biophys Res Commun 303:1028-33
Zhao, Runxiang; Fu, Xueqi; Li, Qingshan et al. (2003) Specific interaction of protein tyrosine phosphatase-MEG2 with phosphatidylserine. J Biol Chem 278:22609-14
Xiong, Huaqi; Chen, Yongxiong; Yi, Yajun et al. (2002) A novel gene encoding a TIG multiple domain protein is a positional candidate for autosomal recessive polycystic kidney disease. Genomics 80:96-104
Mishra, Ashwini K; Zhang, Aihua; Niu, Tianqi et al. (2002) Substrate specificity of protein tyrosine phosphatase: differential behavior of SHP-1 and SHP-2 towards signal regulation protein SIRPalpha1. J Cell Biochem 84:840-6
Zhao, Runxiang; Guerrah, Abdelmadjid; Tang, Hua et al. (2002) Cell surface glycoprotein PZR is a major mediator of concanavalin A-induced cell signaling. J Biol Chem 277:7882-8
Xu, Ming-jiang; Zhao, Runxiang; Cao, Hongxi et al. (2002) SPAP2, an Ig family receptor containing both ITIMs and ITAMs. Biochem Biophys Res Commun 293:1037-46
Qi, Ying; Zhao, Runxiang; Cao, Hongxi et al. (2002) Purification and characterization of protein tyrosine phosphatase PTP-MEG2. J Cell Biochem 86:79-89
Zhao, R; Qi, Y; Chen, J et al. (2001) FYVE-DSP2, a FYVE domain-containing dual specificity protein phosphatase that dephosphorylates phosphotidylinositol 3-phosphate. Exp Cell Res 265:329-38

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