Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA075575-06
Application #
2654306
Study Section
General Medicine A Subcommittee 2 (GMA)
Program Officer
Finerty, John F
Project Start
1991-09-30
Project End
2000-01-31
Budget Start
1998-02-01
Budget End
1999-01-31
Support Year
6
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Texas MD Anderson Cancer Center
Department
Microbiology/Immun/Virology
Type
Other Domestic Higher Education
DUNS #
001910777
City
Houston
State
TX
Country
United States
Zip Code
77030
Byrne, Scott N; Limon-Flores, Alberto Y; Ullrich, Stephen E (2008) Mast cell migration from the skin to the draining lymph nodes upon ultraviolet irradiation represents a key step in the induction of immune suppression. J Immunol 180:4648-55
Sreevidya, Coimbatore S; Khaskhely, Noor M; Fukunaga, Atsushi et al. (2008) Inhibition of photocarcinogenesis by platelet-activating factor or serotonin receptor antagonists. Cancer Res 68:3978-84
Fukunaga, Atsushi; Khaskhely, Noor M; Sreevidya, Coimbatore S et al. (2008) Dermal dendritic cells, and not Langerhans cells, play an essential role in inducing an immune response. J Immunol 180:3057-64
Ullrich, Stephen E (2007) Sunlight and skin cancer: lessons from the immune system. Mol Carcinog 46:629-33
Ullrich, Stephen E; Nghiem, Dat X; Khaskina, Polina (2007) Suppression of an established immune response by UVA--a critical role for mast cells. Photochem Photobiol 83:1095-100
Wolf, Peter; Nghiem, Dat X; Walterscheid, Jeffrey P et al. (2006) Platelet-activating factor is crucial in psoralen and ultraviolet A-induced immune suppression, inflammation, and apoptosis. Am J Pathol 169:795-805
Matsumura, Yumi; Byrne, Scott N; Nghiem, Dat X et al. (2006) A role for inflammatory mediators in the induction of immunoregulatory B cells. J Immunol 177:4810-7
Walterscheid, Jeffrey P; Nghiem, Dat X; Kazimi, Nasser et al. (2006) Cis-urocanic acid, a sunlight-induced immunosuppressive factor, activates immune suppression via the 5-HT2A receptor. Proc Natl Acad Sci U S A 103:17420-5
Ullrich, Stephen E (2005) Mechanisms underlying UV-induced immune suppression. Mutat Res 571:185-205
Ramos, Gerardo; Kazimi, Nasser; Nghiem, Dat X et al. (2004) Platelet activating factor receptor binding plays a critical role in jet fuel-induced immune suppression. Toxicol Appl Pharmacol 195:331-8

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