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Hoogervorst, Esther M; van Oostrom, Conny Th M; Beems, Rudolf B et al. (2004) p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice. Cancer Res 64:5118-26
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Wijnhoven, Susan W P; van Steeg, Harry (2003) Transgenic and knockout mice for DNA repair functions in carcinogenesis and mutagenesis. Toxicology 193:171-87
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Hoogervorst, Esther M; de Vries, Annemieke; Beems, Rudolf B et al. (2003) Combined oral benzo[a]pyrene and inhalatory ozone exposure have no effect on lung tumor development in DNA repair-deficient Xpa mice. Carcinogenesis 24:613-9
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Dolle, Martijn E T; Snyder, Wendy K; Dunson, David B et al. (2002) Mutational fingerprints of aging. Nucleic Acids Res 30:545-9
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Giese, Heidi; Snyder, Wendy K; van Oostrom, Conny et al. (2002) Age-related mutation accumulation at a lacZ reporter locus in normal and tumor tissues of Trp53-deficient mice. Mutat Res 514:153-63
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van Steeg, H (2001) The role of nucleotide excision repair and loss of p53 in mutagenesis and carcinogenesis. Toxicol Lett 120:209-19
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Klein, J C; Beems, R B; Zwart, P E et al. (2001) Intestinal toxicity and carcinogenic potential of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in DNA repair deficient XPA-/- mice. Carcinogenesis 22:619-26
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van Steeg, H; de Vries, A; van Oostrom CTh et al. (2001) DNA repair-deficient Xpa and Xpa/p53+/- knock-out mice: nature of the models. Toxicol Pathol 29 Suppl:109-16
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van Oostrom, C T; Boeve, M; van Den Berg, J et al. (1999) Effect of heterozygous loss of p53 on benzo[a]pyrene-induced mutations and tumors in DNA repair-deficient XPA mice. Environ Mol Mutagen 34:124-30
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