Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA076274-07
Application #
6698042
Study Section
Special Emphasis Panel (ZRG1-CAMP (01))
Program Officer
Mccarthy, Susan A
Project Start
1997-12-16
Project End
2007-12-31
Budget Start
2004-01-01
Budget End
2004-12-31
Support Year
7
Fiscal Year
2004
Total Cost
$274,480
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
006471700
City
Rochester
State
MN
Country
United States
Zip Code
55905
Mantchev, George T; Cortesao, Catarina S; Rebrovich, Michelle et al. (2007) TACI is required for efficient plasma cell differentiation in response to T-independent type 2 antigens. J Immunol 179:2282-8
Bischof, Daniela; Elsawa, Sherine F; Mantchev, George et al. (2006) Selective activation of TACI by syndecan-2. Blood 107:3235-42
Diaz-de-Durana, Yaiza; Mantchev, George T; Bram, Richard J et al. (2006) TACI-BLyS signaling via B-cell-dendritic cell cooperation is required for naive CD8+ T-cell priming in vivo. Blood 107:594-601
O'Connor, Brian P; Raman, Vanitha S; Erickson, Loren D et al. (2004) BCMA is essential for the survival of long-lived bone marrow plasma cells. J Exp Med 199:91-8
von Bulow, G U; van Deursen, J M; Bram, R J (2001) Regulation of the T-independent humoral response by TACI. Immunity 14:573-82
von Bulow, G U; Russell, H; Copeland, N G et al. (2000) Molecular cloning and functional characterization of murine transmembrane activator and CAML interactor (TACI) with chromosomal localization in human and mouse. Mamm Genome 11:628-32