Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA080171-04
Application #
6489187
Study Section
Radiation Study Section (RAD)
Program Officer
Pelroy, Richard
Project Start
1999-01-22
Project End
2002-06-30
Budget Start
2002-01-01
Budget End
2002-06-30
Support Year
4
Fiscal Year
2002
Total Cost
$10,355
Indirect Cost
Name
Albert Einstein College of Medicine
Department
Pathology
Type
Schools of Medicine
DUNS #
009095365
City
Bronx
State
NY
Country
United States
Zip Code
10461
Lu, Yi; Luo, Zhonghui; Bregman, David B (2002) RNA polymerase II large subunit is cleaved by caspases during DNA damage-induced apoptosis. Biochem Biophys Res Commun 296:954-61
Luo, Z; Zheng, J; Lu, Y et al. (2001) Ultraviolet radiation alters the phosphorylation of RNA polymerase II large subunit and accelerates its proteasome-dependent degradation. Mutat Res 486:259-74
Lu, Y; Lian, H; Sharma, P et al. (2001) Disruption of the Cockayne syndrome B gene impairs spontaneous tumorigenesis in cancer-predisposed Ink4a/ARF knockout mice. Mol Cell Biol 21:1810-8
Lu, Y; Mani, S; Kandimalla, E R et al. (2001) The Cockayne syndrome group B DNA repair protein as an anti-cancer target. Int J Oncol 19:1089-97
Bregman, D B; Pestell, R G; Kidd, V J (2000) Cell cycle regulation and RNA polymerase II. Front Biosci 5:D244-57