Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA081439-05
Application #
6633395
Study Section
Metabolic Pathology Study Section (MEP)
Program Officer
Okano, Paul
Project Start
1999-05-14
Project End
2005-02-28
Budget Start
2003-03-01
Budget End
2005-02-28
Support Year
5
Fiscal Year
2003
Total Cost
$300,865
Indirect Cost
Name
Johns Hopkins University
Department
Pathology
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Shi, Chanjuan; Parker, Antony R; Hua, Li et al. (2008) Anti-gene padlocks eliminate Escherichia coli based on their genotype. J Antimicrob Chemother 61:262-72
Parker, Antony R; Sieber, Oliver M; Shi, Chanjuan et al. (2005) Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair. Carcinogenesis 26:2010-8
Murphy, Kathleen M; Berg, Karin D; Eshleman, James R (2005) Sequencing of genomic DNA by combined amplification and cycle sequencing reaction. Clin Chem 51:35-9
Shi, Chanjuan; Eshleman, Susan H; Jones, Dana et al. (2004) LigAmp for sensitive detection of single-nucleotide differences. Nat Methods 1:141-7
Parker, A R; Leonard, C P; Hua, L et al. (2004) A subgroup of microsatellite stable colorectal cancers has elevated mutation rates and different responses to alkylating and oxidising agents. Br J Cancer 90:1666-71
Parker, Antony R; O'Meally, Robert N; Sahin, Fikret et al. (2003) Defective human MutY phosphorylation exists in colorectal cancer cell lines with wild-type MutY alleles. J Biol Chem 278:47937-45
Parker, A R; Eshleman, J R (2003) Human MutY: gene structure, protein functions and interactions, and role in carcinogenesis. Cell Mol Life Sci 60:2064-83
Parker, Antony R; O'Meally, Robert N; Oliver, Dwight H et al. (2002) 8-Hydroxyguanosine repair is defective in some microsatellite stable colorectal cancer cells. Cancer Res 62:7230-3
Murphy, Kathleen M; Eshleman, James R (2002) Simultaneous sequencing of multiple polymerase chain reaction products and combined polymerase chain reaction with cycle sequencing in single reactions. Am J Pathol 161:27-33
Lee, S C; Berg, K D; Sherman, M E et al. (2001) Microsatellite instability is infrequent in medullary breast cancer. Am J Clin Pathol 115:823-7

Showing the most recent 10 out of 12 publications