Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA081506-05S1
Application #
6862528
Study Section
Metabolic Pathology Study Section (MEP)
Program Officer
Rosenfeld, Bobby
Project Start
2000-02-23
Project End
2005-01-31
Budget Start
2004-02-12
Budget End
2005-01-31
Support Year
5
Fiscal Year
2004
Total Cost
$59,400
Indirect Cost
Name
Tulane University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
053785812
City
New Orleans
State
LA
Country
United States
Zip Code
70118
Zeimet, Alain G; Fiegl, Heidi; Goebel, Georg et al. (2011) DNA ploidy, nuclear size, proliferation index and DNA-hypomethylation in ovarian cancer. Gynecol Oncol 121:24-31
Lacey, Michelle R; Ehrlich, Melanie (2009) Modeling dependence in methylation patterns with application to ovarian carcinomas. Stat Appl Genet Mol Biol 8:Article 40
Shao, Chunbo; Lacey, Michelle; Dubeau, Louis et al. (2009) Hemimethylation footprints of DNA demethylation in cancer. Epigenetics 4:165-75
Ehrlich, Melanie; Sanchez, Cecilia; Shao, Chunbo et al. (2008) ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation. Autoimmunity 41:253-71
Ehrlich, M (2006) Cancer-linked DNA hypomethylation and its relationship to hypermethylation. Curr Top Microbiol Immunol 310:251-74
Ehrlich, M; Woods, C B; Yu, M C et al. (2006) Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors. Oncogene 25:2636-45
Grunau, Christoph; Sanchez, Cecilia; Ehrlich, Melanie et al. (2005) Frequent DNA hypomethylation of human juxtacentromeric BAGE loci in cancer. Genes Chromosomes Cancer 43:11-24
Nishiyama, Rie; Qi, Lixin; Tsumagari, Koji et al. (2005) A DNA repeat, NBL2, is hypermethylated in some cancers but hypomethylated in others. Cancer Biol Ther 4:440-8
Gisselsson, David; Shao, Chunbo; Tuck-Muller, Cathy M et al. (2005) Interphase chromosomal abnormalities and mitotic missegregation of hypomethylated sequences in ICF syndrome cells. Chromosoma 114:118-26
Ehrlich, M (2005) The controversial denouement of vertebrate DNA methylation research. Biochemistry (Mosc) 70:568-75

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