|
Huang, Chengyun; Liu, Yang; Rokita, Steven E (2016) Targeting duplex DNA with the reversible reactivity of quinone methides. Signal Transduct Target Ther 1:
|
|
Liu, Yang; Rokita, Steven E (2012) Inducible alkylation of DNA by a quinone methide-peptide nucleic acid conjugate. Biochemistry 51:1020-7
|
|
Rossiter, Clifford S; Modica, Emilia; Kumar, Dalip et al. (2011) Few constraints limit the design of quinone methide-oligonucleotide self-adducts for directing DNA alkylation. Chem Commun (Camb) 47:1476-8
|
|
Weinert, Emily E; Dondi, Ruggero; Colloredo-Melz, Stefano et al. (2006) Substituents on quinone methides strongly modulate formation and stability of their nucleophilic adducts. J Am Chem Soc 128:11940-7
|
|
Weinert, Emily E; Frankenfield, Kristen N; Rokita, Steven E (2005) Time-dependent evolution of adducts formed between deoxynucleosides and a model quinone methide. Chem Res Toxicol 18:1364-70
|
|
Kumar, Dalip; Veldhuyzen, Willem F; Zhou, Qibing et al. (2004) Conjugation of a hairpin pyrrole-imidazole polyamide to a quinone methide for control of DNA cross-linking. Bioconjug Chem 15:915-22
|
|
Zhou, Qibing; Rokita, Steven E (2003) A general strategy for target-promoted alkylation in biological systems. Proc Natl Acad Sci U S A 100:15452-7
|
|
Veldhuyzen, Willem F; Pande, Praveen; Rokita, Steven E (2003) A transient product of DNA alkylation can be stabilized by binding localization. J Am Chem Soc 125:14005-13
|
|
Veldhuyzen, W F; Lam, Y F; Rokita, S E (2001) 2'-Deoxyguanosine reacts with a model quinone methide at multiple sites. Chem Res Toxicol 14:1345-51
|
|
Zhou, Q; Pande, P; Johnson, A E et al. (2001) Sequence-specific delivery of a quinone methide intermediate to the major groove of DNA. Bioorg Med Chem 9:2347-54
|
