Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA082525-02
Application #
6173788
Study Section
Pathology B Study Section (PTHB)
Program Officer
Spalholz, Barbara A
Project Start
1999-07-01
Project End
2004-04-30
Budget Start
2000-05-01
Budget End
2001-04-30
Support Year
2
Fiscal Year
2000
Total Cost
$224,198
Indirect Cost

  Institution

Name
University of Cincinnati
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221

  Publications

Angus, Steven P; Solomon, David A; Kuschel, Lioba et al. (2003) Retinoblastoma tumor suppressor: analyses of dynamic behavior in living cells reveal multiple modes of regulation. Mol Cell Biol 23:8172-88
Solomon, David A; Wang, Ying; Fox, Sejal R et al. (2003) Cyclin D1 splice variants. Differential effects on localization, RB phosphorylation, and cellular transformation. J Biol Chem 278:30339-47
Siddiqui, Hasan; Solomon, David A; Gunawardena, Ranjaka W et al. (2003) Histone deacetylation of RB-responsive promoters: requisite for specific gene repression but dispensable for cell cycle inhibition. Mol Cell Biol 23:7719-31
Reisman, David N; Strobeck, Matthew W; Betz, Bryan L et al. (2002) Concomitant down-regulation of BRM and BRG1 in human tumor cell lines: differential effects on RB-mediated growth arrest vs CD44 expression. Oncogene 21:1196-207
Betz, Bryan L; Strobeck, Matthew W; Reisman, David N et al. (2002) Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB. Oncogene 21:5193-203
Strobeck, Matthew W; Reisman, David N; Gunawardena, Ranjaka W et al. (2002) Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling. J Biol Chem 277:4782-9
Angus, Steven P; Fribourg, Anne F; Markey, Michael P et al. (2002) Active RB elicits late G1/S inhibition. Exp Cell Res 276:201-13
Angus, Steven P; Wheeler, Linda J; Ranmal, Sejal A et al. (2002) Retinoblastoma tumor suppressor targets dNTP metabolism to regulate DNA replication. J Biol Chem 277:44376-84
Strobeck, M W; DeCristofaro, M F; Banine, F et al. (2001) The BRG-1 subunit of the SWI/SNF complex regulates CD44 expression. J Biol Chem 276:9273-8
Sever-Chroneos, Z; Angus, S P; Fribourg, A F et al. (2001) Retinoblastoma tumor suppressor protein signals through inhibition of cyclin-dependent kinase 2 activity to disrupt PCNA function in S phase. Mol Cell Biol 21:4032-45

Showing the most recent 10 out of 14 publications