Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
3R01CA107166-01S1
Application #
6948943
Study Section
Tumor Progression and Metastasis Study Section (TPM)
Program Officer
Rosenfeld, Bobby
Project Start
2004-04-07
Project End
2009-03-31
Budget Start
2004-04-07
Budget End
2005-03-31
Support Year
1
Fiscal Year
2004
Total Cost
$37,266
Indirect Cost

  Institution

Name
University of California Los Angeles
Department
Pharmacology
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095

  Publications

Ruscetti, M; Dadashian, E L; Guo, W et al. (2016) HDAC inhibition impedes epithelial-mesenchymal plasticity and suppresses metastatic, castration-resistant prostate cancer. Oncogene 35:3781-95
Ruscetti, Marcus; Quach, Bill; Dadashian, Eman L et al. (2015) Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis. Cancer Res 75:2749-59
Garcia, Alejandro J; Ruscetti, Marcus; Arenzana, Teresita L et al. (2014) Pten null prostate epithelium promotes localized myeloid-derived suppressor cell expansion and immune suppression during tumor initiation and progression. Mol Cell Biol 34:2017-28
Hill, Reginald; Li, Yunfeng; Tran, Linh M et al. (2012) Cell intrinsic role of COX-2 in pancreatic cancer development. Mol Cancer Ther 11:2127-37
Hübner, Anette; Mulholland, David J; Standen, Claire L et al. (2012) JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate. Proc Natl Acad Sci U S A 109:12046-51
Jiao, Jing; Hindoyan, Antreas; Wang, Shunyou et al. (2012) Identification of CD166 as a surface marker for enriching prostate stem/progenitor and cancer initiating cells. PLoS One 7:e42564
Mulholland, David J; Kobayashi, Naoko; Ruscetti, Marcus et al. (2012) Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. Cancer Res 72:1878-89
Tran, Linh M; Chang, Chun-Ju; Plaisier, Seema et al. (2012) Determining PTEN functional status by network component deduced transcription factor activities. PLoS One 7:e31053
Mulholland, David J; Tran, Linh M; Li, Yunfeng et al. (2011) Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell 19:792-804
Lukacs, Rita U; Memarzadeh, Sanaz; Wu, Hong et al. (2010) Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation. Cell Stem Cell 7:682-93

Showing the most recent 10 out of 30 publications