Little is known about the disease prevention behavior of Chinese in North America, and relatively few studies have addressed cancer control in this group. However, Chinese Americans/Canadians have a much higher incidence of liver cancer than non-Latino Whites. This excess risk is attributable to high rates of hepatitis B virus (HBV) infection combined with low levels of hepatitis B vaccination coverage. One critical area for the strategic development of health literacy among Asian and other immigrant groups is the design and evaluation of culturally appropriate English as a second language (ESL) curricula. The goal of our research is to increase the proportion of Chinese adults who have been tested for evidence of HBV infection. Our objective is to conduct a group-randomized controlled trial to evaluate the acceptability, feasibility, and effectiveness of a liver cancer control educational intervention for Chinese attending ESL classes. Our study will be conducted in Seattle, Washington and Vancouver, British Columbia. The Health Behavior Framework, findings from a previous hepatitis B qualitative study, and focus groups of ESL teachers as well as students will be used to develop the hepatitis B educational program. An intervention trial will be conducted with ESL classes as the unit of randomization. Sixty ESL classes will be randomized to experimental or control status. Six hundred Chinese men and women aged 18-64 years will participate in the trial. The experimental group will receive a hepatitis B intervention and the control group will receive a heart disease intervention. Educational components will include an ESL curriculum as well as a pamphlet. Participants will complete a self-administered baseline survey, just prior to receiving health education. Outcome evaluation will be based on data from an in-person follow-up survey and medical record verification. Our primary outcome will be HBV serologic testing. Knowledge about key hepatitis B facts will be examined as a secondary outcome.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA113663-05
Application #
7618204
Study Section
Community-Level Health Promotion Study Section (CLHP)
Program Officer
Kobrin, Sarah
Project Start
2005-05-09
Project End
2011-10-31
Budget Start
2009-05-01
Budget End
2011-10-31
Support Year
5
Fiscal Year
2009
Total Cost
$306,533
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
078200995
City
Seattle
State
WA
Country
United States
Zip Code
98109
Taylor, Vicky M; Gregory Hislop, T; Bajdik, Christopher et al. (2011) Hepatitis B ESL education for Asian immigrants. J Community Health 36:35-41
Tu R, Shin-Ping; Li, Lin; Tsai, Jenny Hsin-Chun et al. (2009) A cross-border comparison of hepatitis B testing among chinese residing in Canada and the United States. Asian Pac J Cancer Prev 10:483-90
Hislop, T Gregory; Bajdik, Chris D; Teh, Chong et al. (2009) Hepatitis B testing and vaccination in immigrants attending English as a second language classes in British Columbia, Canada. Asian Pac J Cancer Prev 10:997-1002
Taylor, Vicky M; Hislop, T Gregory; Tu, Shin-Ping et al. (2009) Evaluation of a hepatitis B lay health worker intervention for Chinese Americans and Canadians. J Community Health 34:165-72
Woodall, Erica D; Taylor, Victoria M; Teh, Chong et al. (2009) Sources of health information among Chinese immigrants to the Pacific Northwest. J Cancer Educ 24:334-40
Taylor, Victoria M; Teh, Chong; Lam, Wendy et al. (2009) Evaluation of a hepatitis B educational ESL curriculum for Chinese immigrants. Can J Public Health 100:463-6
Coronado, Gloria D; Taylor, Victoria M; Hislop, T Gregory et al. (2008) Opinions from ESL instructors and students about curricula on hepatitis B for use in immigrant communities. J Cancer Educ 23:161-6
Taylor, Victoria M; Cripe, Swee May; Acorda, Elizabeth et al. (2008) Development of an ESL curriculum to educate Chinese immigrants about physical activity. J Immigr Minor Health 10:379-87
Taylor, Victoria M; Coronado, Gloria; Acorda, Elizabeth et al. (2008) Development of an ESL curriculum to educate Chinese immigrants about hepatitis B. J Community Health 33:217-24
Hislop, T Gregory; Teh, Chong; Low, Angeline et al. (2008) Knowledge and behaviour regarding heart disease prevention in Chinese Canadian immigrants. Can J Public Health 99:232-5

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