Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Project (R01)
Project #
5R01CA117821-08
Application #
7320292
Study Section
Arthritis, Connective Tissue and Skin Study Section (ACTS)
Program Officer
Malone, Winfred F
Project Start
2000-05-05
Project End
2010-11-30
Budget Start
2007-12-01
Budget End
2008-11-30
Support Year
8
Fiscal Year
2008
Total Cost
$287,986
Indirect Cost

  Institution

Name
University of Rochester
Department
Dermatology
Type
Schools of Dentistry
DUNS #
041294109
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Mantel, Alon; Carpenter-Mendini, Amanda; VanBuskirk, JoAnne et al. (2014) Aldo-keto reductase 1C3 is overexpressed in skin squamous cell carcinoma (SCC) and affects SCC growth via prostaglandin metabolism. Exp Dermatol 23:573-8
Mantel, Alon; Carpenter-Mendini, Amanda B; Vanbuskirk, Joanne B et al. (2012) Aldo-keto reductase 1C3 is expressed in differentiated human epidermis, affects keratinocyte differentiation, and is upregulated in atopic dermatitis. J Invest Dermatol 132:1103-10
Brouxhon, Sabine; Kyrkanides, Stephanos; O'Banion, M Kerry et al. (2007) Sequential down-regulation of E-cadherin with squamous cell carcinoma progression: loss of E-cadherin via a prostaglandin E2-EP2 dependent posttranslational mechanism. Cancer Res 67:7654-64
Brouxhon, Sabine; Konger, Raymond L; VanBuskirk, JoAnne et al. (2007) Deletion of prostaglandin E2 EP2 receptor protects against ultraviolet-induced carcinogenesis, but increases tumor aggressiveness. J Invest Dermatol 127:439-46