We propose to continue for a further two years the screening and followup study of IV drug users at risk for AIDS which was funded by NIDA in October 1986. They study serves as the principal HIV screening mechanism for drug users in treatment in San Francisco. At present, it also provides the only clinical referral available for seropositive drug users. The principal aims of the study are: 1) To examine the changing prevalence of HIV infection in intravenous drug users, in San Francisco as a whole and in different user groups, and in particular in different ethnic populations. 2) To study the association of HIV infection with demographic, behavioral and clinical characteristics of drug users, and to use HIV prevalence information to evaluate public health interventions aimed at stopping the spread of HIV. 3) To study HIV infection and its progression to clinical AIDS in a prospective study of 150 seropositive users and 100 seronegative controls.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA004363-04
Application #
3209918
Study Section
(SRCD)
Project Start
1986-09-30
Project End
1990-08-31
Budget Start
1989-09-01
Budget End
1990-08-31
Support Year
4
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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Hahn, Judith A; Bangsberg, David R; McFarland, William et al. (2004) HIV seroconversion among the homeless and marginally housed in San Francisco: a ten-year study. J Acquir Immune Defic Syndr 37:1616-9
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Hahn, J A; Vranizan, K M; Moss, A R (1997) Who uses needle exchange? A study of injection drug users in treatment in San Francisco, 1989-1990. J Acquir Immune Defic Syndr Hum Retrovirol 15:157-64
Pilote, L; Tulsky, J P; Zolopa, A R et al. (1996) Tuberculosis prophylaxis in the homeless. A trial to improve adherence to referral. Arch Intern Med 156:161-5
Zolopa, A R; Hahn, J A; Gorter, R et al. (1994) HIV and tuberculosis infection in San Francisco's homeless adults. Prevalence and risk factors in a representative sample. JAMA 272:455-61
Shiboski, C H; Hilton, J F; Greenspan, D et al. (1994) HIV-related oral manifestations in two cohorts of women in San Francisco. J Acquir Immune Defic Syndr 7:964-71
Moss, A R; Vranizan, K; Gorter, R et al. (1994) HIV seroconversion in intravenous drug users in San Francisco, 1985-1990. AIDS 8:223-31
Moss, A R; Vranizan, K (1992) Charting the epidemic: the case study of HIV screening of injecting drug users in San Francisco, 1985-1990. Br J Addict 87:467-71
Wolfe, H; Vranizan, K M; Gorter, R G et al. (1992) Crack use and human immunodeficiency virus infection among San Francisco intravenous drug users. Sex Transm Dis 19:111-4

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