Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
7R01DA004975-02
Application #
3210851
Study Section
Pharmacology I Research Subcommittee (DABR)
Project Start
1990-01-01
Project End
1992-02-29
Budget Start
1990-01-01
Budget End
1990-02-28
Support Year
2
Fiscal Year
1989
Total Cost
Indirect Cost
Name
University of Pittsburgh
Department
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Aizenman, E; Reynolds, I J (1992) Modulation of NMDA excitotoxicity by redox reagents. Ann N Y Acad Sci 648:125-31
Aizenman, E; Hartnett, K A; Zhong, C et al. (1992) Interaction of the putative essential nutrient pyrroloquinoline quinone with the N-methyl-D-aspartate receptor redox modulatory site. J Neurosci 12:2362-9
Aizenman, E; Tang, L H; Reynolds, I J (1991) Effects of nicotinic agonists on the NMDA receptor. Brain Res 551:355-7
Reynolds, I J; Rush, E A; Aizenman, E (1990) Reduction of NMDA receptors with dithiothreitol increases [3H]-MK-801 binding and NMDA-induced Ca2+ fluxes. Br J Pharmacol 101:178-82
Aizenman, E; Hartnett, K A; Reynolds, I J (1990) Oxygen free radicals regulate NMDA receptor function via a redox modulatory site. Neuron 5:841-6
Aizenman, E; White, W F; Loring, R H et al. (1990) A 3,4-dihydroxyphenylalanine oxidation product is a non-N-methyl-D-aspartate glutamatergic agonist in rat cortical neurons. Neurosci Lett 116:168-71
Aizenman, E; Loring, R H; Lipton, S A (1990) Blockade of nicotinic responses in rat retinal ganglion cells by neuronal bungarotoxin. Brain Res 517:209-14