Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA005305-09
Application #
2117558
Study Section
Drug Abuse Clinical and Behavioral Research Review Committee (DACB)
Project Start
1987-09-30
Project End
1997-11-30
Budget Start
1995-12-10
Budget End
1996-11-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Rutgers University
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
038633251
City
New Brunswick
State
NJ
Country
United States
Zip Code
08901
Lau, Chyan E; Sun, Lei (2002) The pharmacokinetic determinants of the frequency and pattern of intravenous cocaine self-administration in rats by pharmacokinetic modeling. Drug Metab Dispos 30:254-61
Sun, L; Lau, C E (2001) Simultaneous pharmacokinetic modeling of cocaine and its metabolites, norcocaine and benzoylecgonine, after intravenous and oral administration in rats. Drug Metab Dispos 29:1183-9
Sun, L; Lau, C E (2001) Arteriovenous serum cocaine concentration difference after intravenous bolus injection and constant-rate infusions: relation to pharmacodynamic estimates in rats. Eur J Pharm Sci 14:261-9
Wang, Q; Simpao, A; Sun, L et al. (2001) Contribution of the active metabolite, norcocaine, to cocaine's effects after intravenous and oral administration in rats: pharmacodynamics. Psychopharmacology (Berl) 153:341-52
Falk, J L; D'Mello, K; Lau, C E (2001) Two procedures establishing preference for oral cocaine and lidocaine solutions which do not use an associative history with a reinforcer. Behav Pharmacol 12:117-23
Lau, C E; Sun, L; Wang, Q et al. (2000) Oral cocaine pharmacokinetics and pharmacodynamics in a cumulative-dose regimen: pharmacokinetic-pharmacodynamic modeling of concurrent operant and spontaneous behavior within an operant context. J Pharmacol Exp Ther 295:634-43
Sun, L; Hall, G; Lau, C E (2000) High-performance liquid chromatographic determination of cocaine and its metabolites in serum microsamples with fluorimetric detection and its application to pharmacokinetics in rats. J Chromatogr B Biomed Sci Appl 745:315-23
Lau, C E; Ma, F; Foster, D M et al. (1999) Pharmacokinetic-pharmacodynamic modeling of the psychomotor stimulant effect of cocaine after intravenous administration: timing performance deficits. J Pharmacol Exp Ther 288:535-43
Lobarinas, E; Falk, J L (1999) Dose-dependent effects but not sensitization of DRL 45-s performance by oral d-amphetamine with cumulative- and repeated-dosing regimens. Behav Pharmacol 10:739-46
Ma, F; Falk, J L; Lau, C E (1999) Cocaine pharmacodynamics after intravenous and oral administration in rats: relation to pharmacokinetics. Psychopharmacology (Berl) 144:323-32

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