Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
3R01DA007319-02S1
Application #
3213978
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1992-05-01
Project End
1995-04-30
Budget Start
1993-05-01
Budget End
1994-04-30
Support Year
2
Fiscal Year
1993
Total Cost
Indirect Cost
Name
St. Joseph's Hosp/Medical Center (Phoenix)
Department
Type
DUNS #
City
Phoenix
State
AZ
Country
United States
Zip Code
85013
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Ke, L; Eisenhour, C M; Bencherif, M et al. (1998) Effects of chronic nicotine treatment on expression of diverse nicotinic acetylcholine receptor subtypes. I. Dose- and time-dependent effects of nicotine treatment. J Pharmacol Exp Ther 286:825-40
Lukas, R J; Eisenhour, C M (1996) Interactions between tachykinins and diverse, human nicotinic acetylcholine receptor subtypes. Neurochem Res 21:1245-57
Quik, M; Choremis, J; Komourian, J et al. (1996) Similarity between rat brain nicotinic alpha-bungarotoxin receptors and stably expressed alpha-bungarotoxin binding sites. J Neurochem 67:145-54
Ke, L; Lukas, R J (1996) Effects of steroid exposure on ligand binding and functional activities of diverse nicotinic acetylcholine receptor subtypes. J Neurochem 67:1100-12
Lukas, R J (1995) Diversity and patterns of regulation of nicotinic receptor subtypes. Ann N Y Acad Sci 757:153-68
Bencherif, M; Fowler, K; Lukas, R J et al. (1995) Mechanisms of up-regulation of neuronal nicotinic acetylcholine receptors in clonal cell lines and primary cultures of fetal rat brain. J Pharmacol Exp Ther 275:987-94
Bencherif, M; Eisenhour, C M; Prince, R J et al. (1995) The ""calcium antagonist"" TMB-8 [3,4,5-trimethoxybenzoic acid 8-(diethylamino)octyl ester] is a potent, non-competitive, functional antagonist at diverse nicotinic acetylcholine receptor subtypes. J Pharmacol Exp Ther 275:1418-26
Puchacz, E; Buisson, B; Bertrand, D et al. (1994) Functional expression of nicotinic acetylcholine receptors containing rat alpha 7 subunits in human SH-SY5Y neuroblastoma cells. FEBS Lett 354:155-9
Bencherif, M; Lukas, R J (1993) Cytochalasin modulation of nicotinic cholinergic receptor expression and muscarinic receptor function in human TE671/RD cells: a possible functional role of the cytoskeleton. J Neurochem 61:852-64