Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA007384-05
Application #
2119895
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1992-03-01
Project End
2000-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington State University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
041485301
City
Pullman
State
WA
Country
United States
Zip Code
99164
Volz, Trent J; Schenk, James O (2005) A comprehensive atlas of the topography of functional groups of the dopamine transporter. Synapse 58:72-94
Volz, Trent J; Bjorklund, Nicole L; Schenk, James O (2005) Methylphenidate analogs with behavioral differences interact differently with arginine residues on the dopamine transporter in rat striatum. Synapse 57:175-8
Robinson, Donita L; Volz, Trent J; Schenk, James O et al. (2005) Acute ethanol decreases dopamine transporter velocity in rat striatum: in vivo and in vitro electrochemical measurements. Alcohol Clin Exp Res 29:746-55
Schenk, James O; Wright, Cortney; Bjorklund, Nicole (2005) Unraveling neuronal dopamine transporter mechanisms with rotating disk electrode voltammetry. J Neurosci Methods 143:41-7
Volz, Trent J; Schenk, James O (2004) L-arginine increases dopamine transporter activity in rat striatum via a nitric oxide synthase-dependent mechanism. Synapse 54:173-82
Volz, Trent J; Kim, M; Schenk, James O (2004) Covalent and noncovalent chemical modifications of arginine residues decrease dopamine transporter activity. Synapse 52:272-82
Schenk, James O; George, Shannon E; Schumacher, Paul Dietrich (2003) What can be learned from studies of multisubstrate mechanisms of neuronal dopamine transport? Eur J Pharmacol 479:223-8
Schenk, James O (2002) The functioning neuronal transporter for dopamine: kinetic mechanisms and effects of amphetamines, cocaine and methylphenidate. Prog Drug Res 59:111-31
Wayment, H K; Schenk, J O; Sorg, B A (2001) Characterization of extracellular dopamine clearance in the medial prefrontal cortex: role of monoamine uptake and monoamine oxidase inhibition. J Neurosci 21:35-44
Earles, C; Schenk, J O (1999) Multisubtrate mechanism for the inward transport of dopamine by the human dopamine transporter expressed in HEK cells and its inhibition by cocaine. Synapse 33:230-8

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