The goal of this research project is to understand the neural and cognitive impairments imposed by perinatal cocaine exposure. We will use a unique, well-established model system that may allow us to gain an increased understanding of the role of cocaine action on the developing brain and cognitive behavior. Specifically, we have reported large metabolic, neuropharmacological, morphological and neurophysiological changes in young rats as a consequence of early olfactory preference conditioning, a form of learning that normally occurs during both human and rat development These established neural features should allow us to identify and understand the basis for any impairments induced by early cocaine exposure.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA007425-02
Application #
3214116
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1991-08-01
Project End
1994-07-31
Budget Start
1992-08-01
Budget End
1993-07-31
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of California Irvine
Department
Type
Schools of Arts and Sciences
DUNS #
161202122
City
Irvine
State
CA
Country
United States
Zip Code
92697