Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA007595-05
Application #
2120075
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1992-01-10
Project End
1996-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Oregon Health and Science University
Department
Type
Organized Research Units
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239

  Publications

Mortensen, Ole V; Larsen, Mads B; Amara, Susan G (2017) MAP Kinase Phosphatase 3 (MKP3) Preserves Norepinephrine Transporter Activity by Modulating ERK1/2 Kinase-Mediated Gene Expression. Front Cell Neurosci 11:253
Wheeler, David S; Underhill, Suzanne M; Stolz, Donna B et al. (2015) Amphetamine activates Rho GTPase signaling to mediate dopamine transporter internalization and acute behavioral effects of amphetamine. Proc Natl Acad Sci U S A 112:E7138-47
Underhill, Suzanne M; Wheeler, David S; Amara, Susan G (2015) Differential regulation of two isoforms of the glial glutamate transporter EAAT2 by DLG1 and CaMKII. J Neurosci 35:5260-70
Hong, Weimin C; Amara, Susan G (2013) Differential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons. FASEB J 27:2995-3007
Larsen, Mads B; Fontana, Andreia C K; Magalhaes, Lizandra G et al. (2011) A catecholamine transporter from the human parasite Schistosoma mansoni with low affinity for psychostimulants. Mol Biochem Parasitol 177:35-41
Larsen, Mads Breum; Sonders, Mark S; Mortensen, Ole Valente et al. (2011) Dopamine transport by the serotonin transporter: a mechanistically distinct mode of substrate translocation. J Neurosci 31:6605-15
Hong, Weimin C; Amara, Susan G (2010) Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding. J Biol Chem 285:32616-26
Fontana, Andréia C K; Sonders, Mark S; Pereira-Junior, Olavo S et al. (2009) Two allelic isoforms of the serotonin transporter from Schistosoma mansoni display electrogenic transport and high selectivity for serotonin. Eur J Pharmacol 616:48-57
Mortensen, Ole V; Amara, Susan G (2006) Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters. J Neurochem 98:1531-40
Mortensen, Ole V; Amara, Susan G (2003) Dynamic regulation of the dopamine transporter. Eur J Pharmacol 479:159-70

Showing the most recent 10 out of 33 publications