To date no randomized controlled trials of syringe exchange have taken place. This research is both an efficacy study and a feasibility study design of a two group randomized clinical trial in which current and former injection drug users are assigned to: (a) being able to use a syringe exchange, or (b) not having access to the syringe exchange and being encouraged to use legal pharmacy sales instead. All subjects are followed up every six months and information is collected with Risk Behavior Assessment, a supplementary questionnaire concerning needle use and procurement, locator information, urine testing for amphetamines, cocaine metabolites, and morphine, and serological testing for markers of Hepatitis B Virus. Markers of Human Immunodeficiency Virus will also be monitored. There will be a Data Safety and Monitoring Board who will be overseeing the progress of the research and will have oversight over the ethical issues involved in this research.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
5R01DA010181-03
Application #
2749129
Study Section
Human Development Research Subcommittee (NIDA)
Project Start
1996-09-15
Project End
1999-07-30
Budget Start
1998-07-31
Budget End
1999-07-30
Support Year
3
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Alaska Anchorage
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
City
Anchorage
State
AK
Country
United States
Zip Code
99514
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Fisher, Dennis G; Reynolds, Grace L; Napper, Lucy E (2010) Use of crystal methamphetamine, Viagra, and sexual behavior. Curr Opin Infect Dis 23:53-6
Johnson, Mark E; Brems, Christiane; Mills, Michael E et al. (2007) Psychiatric symptomatology among individuals in alcohol detoxification treatment. Addict Behav 32:1745-52
Wells, Rebecca; Fisher, Dennis; Fenaughty, Andrea et al. (2006) Hepatitis A prevalence among injection drug users. Clin Lab Sci 19:12-7
Johnson, Mark E; Neal, David B; Brems, Christiane et al. (2006) Depression as measured by the Beck Depression Inventory-II among injecting drug users. Assessment 13:168-77
Reynolds, Grace L; Wells, Rebecca S; Fisher, Dennis G et al. (2006) Health services usage by Alaskan injection drug users. J Ethn Subst Abuse 5:23-34
Fisher, Dennis G; Fenaughty, Andrea M; Cagle, Henry H et al. (2003) Needle exchange and injection drug use frequency: a randomized clinical trial. J Acquir Immune Defic Syndr 33:199-205
Fenaughty, Andrea M (2003) Perceptions of power equality among drug-using women. Women Health 37:91-107
Schlicting, Erin G; Johnson, Mark E; Brems, Christiane et al. (2003) Validity of injecting drug users' self report of hepatitis A, B, and C. Clin Lab Sci 16:99-106
Fisher, Dennis G; Harbke, Colin R; Canty, John R et al. (2002) Needle and syringe cleaning practices among injection drug users. J Drug Educ 32:167-78

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