Cognitive behavioral approaches have strong empirical support from randomized clinical trials in a variety of substance-using populations, but implementation of cognitive-behavioral therapy (CBT) remains rare in clinical practice. Although manuals that provide explicit guidelines for implementation of CBT have been developed and widely distributed, mere availability of these manuals has not been associated with dramatic changes in clinicians' use of CBT and other empirically evaluated therapies. Thus, alternative approaches of making CBT more widely available should be evaluated. CBT's highly structured, didactic, practice-oriented nature may make it extremely well suited to direct access by patients through an interactive, multimedia, and highly individualized computer-assisted training program. The computer-based training program (CBT for CBT) would focus on teaching basic coping skills, presenting examples of effective use of coping skills in a number of realistic situations, and providing opportunities for patients to practice and review new skills. Such a program, if found to be an effective adjunct to drug abuse treatment in community-based programs, would be comparatively inexpensive and straightforward to disseminate and implement in a wide range of programs. Thus, in this Stage 1 behavioral therapies development project, submitted in response to NIDA RFA DA-02-006, we propose to: a. Develop and pilot an individualized, interactive, computer based training program for cognitive behavioral therapy (CBT for CBT) for drug abusers. b. Conduct an initial randomized trial evaluating the feasibility and effectiveness of adding 'CBT for CBT' to treatment as usual in a community based treatment program. In the trial, 80 treatment-seeking, drug-dependent individuals will be randomly assigned to treatment as usual in a community-based clinic OR treatment as usual plus 12 hours of access to the 'CBT for CBT' program over a period of 12 weeks. Primary outcomes will be retention in treatment and reduction in drug use (percent days abstinent, confirmed by urine toxicology screens). The patients' ability to demonstrate coping skills through a role-play evaluation will be a secondary outcome. A six-month follow-up will assess durability and/or delayed emergence of effects.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
1R01DA015969-01
Application #
6587014
Study Section
Special Emphasis Panel (ZDA1-KXN-G (06))
Program Officer
Mcnamara-Spitznas, Cecilia M
Project Start
2002-09-30
Project End
2006-05-31
Budget Start
2002-09-30
Budget End
2003-05-31
Support Year
1
Fiscal Year
2002
Total Cost
$231,966
Indirect Cost
Name
Yale University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Decker, Suzanne E; Morie, Kristen P; Malin-Mayo, Bo et al. (2018) Positive and negative affect in cocaine use disorder treatment: Change across time and relevance to treatment outcome. Am J Addict :
Yip, Sarah W; Worhunsky, Patrick D; Xu, Jiansong et al. (2018) Gray-matter relationships to diagnostic and transdiagnostic features of drug and behavioral addictions. Addict Biol 23:394-402
Carroll, Kathleen M; Nich, Charla; DeVito, Elise E et al. (2018) Galantamine and Computerized Cognitive Behavioral Therapy for Cocaine Dependence: A Randomized Clinical Trial. J Clin Psychiatry 79:
Kiluk, Brian D; Nich, Charla; Buck, Matthew B et al. (2018) Randomized Clinical Trial of Computerized and Clinician-Delivered CBT in Comparison With Standard Outpatient Treatment for Substance Use Disorders: Primary Within-Treatment and Follow-Up Outcomes. Am J Psychiatry 175:853-863
Paris, Manuel; Silva, Michelle; AƱez-Nava, Luis et al. (2018) Culturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial. Am J Public Health 108:1535-1542
Kiluk, Brian D; DeVito, Elise E; Buck, Matthew B et al. (2017) Effect of computerized cognitive behavioral therapy on acquisition of coping skills among cocaine-dependent individuals enrolled in methadone maintenance. J Subst Abuse Treat 82:87-92
Carroll, Kathleen M; Kiluk, Brian D (2017) Cognitive behavioral interventions for alcohol and drug use disorders: Through the stage model and back again. Psychol Addict Behav 31:847-861
Yip, Sarah W; Morie, Kristen P; Xu, Jiansong et al. (2017) Shared microstructural features of behavioral and substance addictions revealed in areas of crossing fibers. Biol Psychiatry Cogn Neurosci Neuroimaging 2:188-195
Montgomery, LaTrice; Carroll, Kathleen M (2017) Comparable efficacy of behavioral and pharmacological treatments among African American and White cocaine users. J Ethn Subst Abuse 16:445-459
Yip, Sarah W; DeVito, Elise E; Kober, Hedy et al. (2016) Anticipatory reward processing among cocaine-dependent individuals with and without concurrent methadone-maintenance treatment: Relationship to treatment response. Drug Alcohol Depend 166:134-42

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