? ? Cigarette smoking is the largest preventable risk factor for morbidity and mortality in developed countries. Despite an increasing number of pharmacological and psychosocial treatments for smoking, over 20% of Americans continue to smoke. The limitations of current interventions point to the need for innovative and powerful behavioral therapies for smoking. Abstinence reinforcement therapy is one such treatment. To apply abstinence reinforcement therapy to smoking, we developed a home-based monitoring system to obtain objective measures of smoking status. The system uses Internet technology to obtain video of smokers providing carbon monoxide samples, which is a simple yet innovative way to verify smoking status on a frequent and sustained basis. Voucher reinforcement produced substantial reductions in smoking and sustained abstinence in heavy smokers. In light of these encouraging data, we are proposing to replicate and extend our current results in a three-year study. The home-based system will allow us to deliver a high dose behavioral treatment during the initial weeks of a quit attempt. This is a critical period: abstinence during the first few weeks of a cessation effort is strongly associated with long-term success, and most smokers relapse within the first week of a quit attempt. Furthermore, several recent studies suggest that experimentally inducing abstinence with voucher reinforcement produces increased motivation to quit and lasting effects, even for smokers with no plans to quit. Voucher reinforcement also lowers ratings on a number of key measures associated with relapse risk. It remains to be seen whether these experimentally induced changes in motivation and relapse risk do, in fact, translate into lower relapse rates. Heavy smokers will be randomly assigned to a voucher reinforcement or a non-contingent voucher reinforcement control condition. We will measure motivation to quit, relapse risk, rates of initial abstinence during treatment, and smoking status at a six-month follow up. The proposed study will be the first to provide valuable data about the relation between voucher-induced changes in key measures of relapse risk and relapse rates in heavy smokers, and the efficacy of applying an intensive behavioral treatment during a critical period of a quit attempt. The home-based voucher program may prove to be rigorous and convenient method to initiate and maintain high levels of abstinence, particularly in high-risk groups. As such, it may hold significant promise as a way to reduce the high rates of morbidity and mortality associated with smoking. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
1R01DA019580-01A2
Application #
7212307
Study Section
Human Development Research Subcommittee (NIDA)
Program Officer
Grossman, Debra
Project Start
2007-04-15
Project End
2010-03-31
Budget Start
2007-04-15
Budget End
2008-03-31
Support Year
1
Fiscal Year
2007
Total Cost
$244,983
Indirect Cost
Name
University of Florida
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
969663814
City
Gainesville
State
FL
Country
United States
Zip Code
32611
Dallery, Jesse; Raiff, Bethany R; Grabinski, Michael J (2013) Internet-based contingency management to promote smoking cessation: a randomized controlled study. J Appl Behav Anal 46:750-64
Raiff, Bethany R; Jarvis, Brantley P; Turturici, Marissa et al. (2013) Acceptability of an Internet-based contingency management intervention for smoking cessation: views of smokers, nonsmokers, and healthcare professionals. Exp Clin Psychopharmacol 21:204-13
Dallery, Jesse; Raiff, Bethany R (2011) Contingency management in the 21st century: technological innovations to promote smoking cessation. Subst Use Misuse 46:10-22
Raiff, Bethany R; Faix, Crystal; Turturici, Marissa et al. (2010) Breath carbon monoxide output is affected by speed of emptying the lungs: implications for laboratory and smoking cessation research. Nicotine Tob Res 12:834-8