This application is being submitted in response to ?NOT-DA-19-003.? There is a critical need to address opioid use, opioid use disorder (OUD), and overdose risk among young adults. In this administrative supplement to R01-DA040488 (PIs: C Latkin, K Tobin), we will apply the network science-based peer mentor and social diffusion approaches that have been refined as part of the parent study ? ?Test, Link, Cure? (TLC) ? to young adults who use opioids. Funds will support the preliminary development and refinement of ?TLC-Young Adults? (TLC-YA). The TLC-YA intervention is an enhancement of TLC that: (1) expands the focus to include opioid- related content, including reduction of overdose risk behaviors and OUD treatment, and (2) tailored to 18-30 year olds who use opioids, via injection or non-injection routes. We will conduct formative research (i.e., focus group interviews and component testing) and a pilot test to guide modifications to the TLC-YA intervention. TLC-YA participants will be recruited by TLC participants, from among their social networks. The TLC-YA intervention will be designed to use minimal resources so that it can be quickly implemented by health departments and community-based organizations (CBOs). The proposed research activities are well-aligned with the NIH HEAL Initiative and address opioid-related behaviors among a high-risk population, i.e., Black young adults in low-income, urban areas.

Public Health Relevance

There is a critical need to address opioid use, opioid use disorder (OUD), and overdose risk among young adults. Efforts to respond to opioid-related problems can be integrated into community-based interventions focused on enhancing HIV and HCV care and treatment. Network science-based approaches are promising for reaching young adults who use opioids through injection or non-injection routes.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Project (R01)
Project #
3R01DA040488-04S2
Application #
9857773
Study Section
Behavioral and Social Consequences of HIV/AIDS Study Section (BSCH)
Program Officer
Flournoy Floyd, Minnjuan Wyncephel
Project Start
2015-08-01
Project End
2021-02-28
Budget Start
2019-03-01
Budget End
2020-02-29
Support Year
4
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21205
Smith, M K; Graham, M; Latkin, C A et al. (2018) Quantifying potentially infectious sharing patterns among people who inject drugs in Baltimore, USA. Epidemiol Infect 146:1845-1853
Latkin, Carl A; Edwards, Catie; Davey-Rothwell, Melissa A et al. (2018) The relationship between drug use settings, roles in the drug economy, and witnessing a drug overdose in Baltimore, Maryland. Subst Abus :1-6
Smith, M Kumi; Graham, Matthew; Latkin, Carl A et al. (2018) Using Contact Patterns to Inform HIV Interventions in Persons Who Inject Drugs in Northern Vietnam. J Acquir Immune Defic Syndr 78:1-8
Rao, Amrita; Tobin, Karin; Davey-Rothwell, Melissa et al. (2017) Social Desirability Bias and Prevalence of Sexual HIV Risk Behaviors Among People Who Use Drugs in Baltimore, Maryland: Implications for Identifying Individuals Prone to Underreporting Sexual Risk Behaviors. AIDS Behav 21:2207-2214