Spontaneous and evoked otoacoustic emissions (SOAEs and EOAEs), of apparent cochlear origin, in the ear canals of human subjects constitute and extremely valuable non-invasive probe of the active nonlinear response of the cochlea which determines detection and processing of low level signals. The generation mechanisms of these emissions may be reversibly manipulated by means of external tones and/or noise (either ipsilateral or contralateral), and by the intake of aspirin. The knowledge of auditory function obtainable from measurements of spontaneous and evoked otoacoustic emissions and associated psychoacoustic measures (detection and discrimination), may be greatly enhanced if measures of all these phenomena can be obtained from individual subjects during such manipulation. To this end comprehensive data on otoacoustic emissions and related psycho-acoustical measures will be obtained from subjects with a variety of emission patterns and the data will be compared with the predictions of cochlear models incorporating both active and nonlinear mechanisms based on recent models incorporating both active and nonlinear mechanisms based on recent research into cochlear processes.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC000307-05
Application #
3216512
Study Section
Hearing Research Study Section (HAR)
Project Start
1985-04-01
Project End
1992-03-31
Budget Start
1990-04-01
Budget End
1991-03-31
Support Year
5
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Purdue University
Department
Type
Schools of Arts and Sciences
DUNS #
072051394
City
West Lafayette
State
IN
Country
United States
Zip Code
47907
Tubis, A; Talmadge, C L; Tong, C (2000) Modeling the temporal behavior of distortion product otoacoustic emissions. J Acoust Soc Am 107:2112-27
Talmadge, C L; Tubis, A; Long, G R et al. (1998) Modeling otoacoustic emission and hearing threshold fine structures. J Acoust Soc Am 104:1517-43
Tubis, A; Talmadge, C L (1998) Ear canal reflectance in the presence of spontaneous otoacoustic emissions. I. Limit-cycle oscillator model. J Acoust Soc Am 103:454-61
Talmadge, C L; Tubis, A; Wit, H P et al. (1991) Are spontaneous otoacoustic emissions generated by self-sustained cochlear oscillators? J Acoust Soc Am 89:2391-9