Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC000722-06
Application #
2125954
Study Section
Hearing Research Study Section (HAR)
Project Start
1991-02-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Louisiana State University Hsc New Orleans
Department
Otolaryngology
Type
Schools of Medicine
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
Ruel, J; Bobbin, R P; Vidal, D et al. (2000) The selective AMPA receptor antagonist GYKI 53784 blocks action potential generation and excitotoxicity in the guinea pig cochlea. Neuropharmacology 39:1959-73
Ruel, J; Chen, C; Pujol, R et al. (1999) AMPA-preferring glutamate receptors in cochlear physiology of adult guinea-pig. J Physiol 518 ( Pt 3):667-80
Nenov, A P; Chen, C; Bobbin, R P (1998) Outward rectifying potassium currents are the dominant voltage activated currents present in Deiters' cells. Hear Res 123:168-82
Parker, M S; Larroque, M L; Campbell, J M et al. (1998) Novel variant of the P2X2 ATP receptor from the guinea pig organ of Corti. Hear Res 121:62-70
Chen, C; Skellett, R A; Fallon, M et al. (1998) Additional pharmacological evidence that endogenous ATP modulates cochlear mechanics. Hear Res 118:47-61
Skellett, R A; Cullen Jr, J K; Fallon, M et al. (1998) Conditioning the auditory system with continuous vs. interrupted noise of equal acoustic energy: is either exposure more protective? Hear Res 116:21-32
Chen, C; Bobbin, R P (1998) P2X receptors in cochlear Deiters' cells. Br J Pharmacol 124:337-44
Chen, C; LeBlanc, C; Bobbin, R P (1997) Differences in the distribution of responses to ATP and acetylcholine between outer hair cells of rat and guinea pig. Hear Res 110:87-94
Nenov, A P; Skellett, R A; Fallon, M et al. (1997) Nitrosoglutathione suppresses cochlear potentials and DPOAEs but not outer hair cell currents or voltage-dependent capacitance. Hear Res 110:77-86
Skellett, R A; Chen, C; Fallon, M et al. (1997) Pharmacological evidence that endogenous ATP modulates cochlear mechanics. Hear Res 111:42-54

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