Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC002273-03
Application #
2127542
Study Section
Hearing Research Study Section (HAR)
Project Start
1994-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Cedars-Sinai Medical Center
Department
Type
DUNS #
075307785
City
Los Angeles
State
CA
Country
United States
Zip Code
90048
Fischel-Ghodsian, N (1999) Genetic factors in aminoglycoside toxicity. Ann N Y Acad Sci 884:99-109
Casano, R A; Johnson, D F; Bykhovskaya, Y et al. (1999) Inherited susceptibility to aminoglycoside ototoxicity: genetic heterogeneity and clinical implications. Am J Otolaryngol 20:151-6
Verhoeven, K; Ensink, R J; Tiranti, V et al. (1999) Hearing impairment and neurological dysfunction associated with a mutation in the mitochondrial tRNASer(UCN) gene. Eur J Hum Genet 7:45-51
Fischel-Ghodsian, N (1999) Mitochondrial deafness mutations reviewed. Hum Mutat 13:261-70
Fischel-Ghodsian, N (1998) Mitochondrial RNA processing and translation: link between mitochondrial mutations and hearing loss? Mol Genet Metab 65:97-104
Fischel-Ghodsian, N (1998) Mitochondrial mutations and hearing loss: paradigm for mitochondrial genetics. Am J Hum Genet 62:15-9
Johnson, D F; Hamon, M; Fischel-Ghodsian, N (1998) Characterization of the human mitochondrial ribosomal S12 gene. Genomics 52:363-8
Johnson, D F; Prezant, T R; Lubavin, B et al. (1998) Isolation of overexpressed yeast genes which prevent aminoglycoside toxicity. Hear Res 120:62-8
Casano, R A; Bykhovskaya, Y; Johnson, D F et al. (1998) Hearing loss due to the mitochondrial A1555G mutation in Italian families. Am J Med Genet 79:388-91
Fischel-Ghodsian, N (1998) Mitochondrial genetics and hearing loss: the missing link between genotype and phenotype. Proc Soc Exp Biol Med 218:1-6

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