Phonation is a component of speech communication with a highly complex interplay of physiological and physical properties. Phonation is the vibratory system in the larynx that changes air flow from the lungs into sound in the throat. The process of vocal fold vibration and the conversion of air flow into sound is insufficiently understood for the purposes of making precise diagnostic decisions in the voice clinic, targeting optimal intervention strategies for voice problems, and achieving high quality articulatory speech synthesis. The long-range goal of this research program is to develop an efficient and highly effective computer model of phonation that takes into account the tissue and flow-acoustic dynamics for both normal and pathological laryngeal conditions. This continuation application focuses on the details of the basic physics dealing with the flow-acoustic interactions and driving intraglottal pressures by using various physical, computational, and tissue models of phonation.
The aims are to 1) extend phonatory modeling to three dimensions with greater geometric complexity, 2) gain a thorough understanding of the aerodynamics and aeroacoustics for steady and pulsatile flows in rigid and moving-wall laryngeal airways, 3) develop detailed predictive models to explain the flow physics of phonation, in parallel with simpler models that are computationally efficient and clinically applicable, and 4) determine the effects of glottal jet flow for normal and pathological conditions of the glottis using an in-vivo canine model. The three types of models (physical, computational, and tissue) are used to cross-validate new information that bridges between basic modeling and real larynx phonation. This research program is a collaboration among laboratories at Bowling Green State University, Purdue University, the University of Toledo, and Washington University in Saint Louis.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
Research Project (R01)
Project #
5R01DC003577-07
Application #
6777473
Study Section
Special Emphasis Panel (ZRG1-BBBP-7 (01))
Program Officer
Shekim, Lana O
Project Start
1998-01-01
Project End
2006-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
7
Fiscal Year
2004
Total Cost
$636,849
Indirect Cost
Name
Bowling Green State University
Department
Psychology
Type
Schools of Allied Health Profes
DUNS #
617407325
City
Bowling Green
State
OH
Country
United States
Zip Code
43403
Fulcher, Lewis P; Scherer, Ronald C; Powell, Travis (2013) Viscous effects in a static physical model of the uniform glottis. J Acoust Soc Am 134:1253-60
Li, Sheng; Scherer, Ronald C; Wan, MingXi et al. (2012) The effect of entrance radii on intraglottal pressure distributions in the divergent glottis. J Acoust Soc Am 131:1371-7
Fulcher, Lewis P; Scherer, Ronald C (2011) Phonation threshold pressure: comparison of calculations and measurements taken with physical models of the vocal fold mucosa. J Acoust Soc Am 130:1597-605
Fulcher, Lewis P; Scherer, Ronald C; Powell, Travis (2011) Pressure distributions in a static physical model of the uniform glottis: entrance and exit coefficients. J Acoust Soc Am 129:1548-53
Fulcher, Lewis P; Scherer, Ronald C; De Witt, Kenneth J et al. (2010) Pressure distributions in a static physical model of the hemilarynx: measurements and computations. J Voice 24:2-20
Khosla, Sid; Murugappan, Shanmugam; Gutmark, Ephraim (2008) What can vortices tell us about vocal fold vibration and voice production. Curr Opin Otolaryngol Head Neck Surg 16:183-7
Garrel, Renaud; Scherer, Ronald; Nicollas, Richard et al. (2008) Using the relaxation oscillations principle for simple phonation modeling. J Voice 22:385-98
Suh, Jungsoo; Frankel, Steven H (2008) Comparing turbulence models for flow through a rigid glottal model. J Acoust Soc Am 123:1237-40
Park, Jong Beom; Mongeau, Luc (2007) Instantaneous orifice discharge coefficient of a physical, driven model of the human larynx. J Acoust Soc Am 121:442-55
Suh, Jungsoo; Frankel, Steven H (2007) Numerical simulation of turbulence transition and sound radiation for flow through a rigid glottal model. J Acoust Soc Am 121:3728-39

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