Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
3R01DE008275-03S1
Application #
3222073
Study Section
Experimental Virology Study Section (EVR)
Project Start
1987-05-01
Project End
1990-08-31
Budget Start
1990-05-01
Budget End
1990-08-31
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Type
Schools of Dentistry
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Navarro, D; Qadri, I; Pereira, L (1993) Transport and secretion of truncated derivatives of herpes simplex virus 1 glycoprotein B. Virology 192:234-45
Navarro, D; Paz, P; Pereira, L (1992) Domains of herpes simplex virus I glycoprotein B that function in virus penetration, cell-to-cell spread, and cell fusion. Virology 186:99-112
Wooden, S K; Li, L J; Navarro, D et al. (1991) Transactivation of the grp78 promoter by malfolded proteins, glycosylation block, and calcium ionophore is mediated through a proximal region containing a CCAAT motif which interacts with CTF/NF-I. Mol Cell Biol 11:5612-23
Navarro, D; Qadri, I; Pereira, L (1991) A mutation in the ectodomain of herpes simplex virus 1 glycoprotein B causes defective processing and retention in the endoplasmic reticulum. Virology 184:253-64
Qadri, I; Gimeno, C; Navarro, D et al. (1991) Mutations in conformation-dependent domains of herpes simplex virus 1 glycoprotein B affect the antigenic properties, dimerization, and transport of the molecule. Virology 180:135-52
Pereira, L; Qadri, I; Navarro, D et al. (1990) Antigenic and structural properties of mutants in herpes simplex virus 1 glycoprotein B. Adv Exp Med Biol 278:165-82
Kohl, S; Strynadka, N C; Hodges, R S et al. (1990) Analysis of the role of antibody-dependent cellular cytotoxic antibody activity in murine neonatal herpes simplex virus infection with antibodies to synthetic peptides of glycoprotein D and monoclonal antibodies to glycoprotein B. J Clin Invest 86:273-8
Pereira, L; Ali, M; Kousoulas, K et al. (1989) Domain structure of herpes simplex virus 1 glycoprotein B: neutralizing epitopes map in regions of continuous and discontinuous residues. Virology 172:11-24
Banks, T; Huo, B; Kousoulas, K et al. (1989) A major neutralizing domain maps within the carboxyl-terminal half of the cleaved cytomegalovirus B glycoprotein. J Gen Virol 70 ( Pt 4):979-85
Kousoulas, K; Arsenakis, M; Pereira, L (1989) A subset of type-specific epitopes map in the amino terminus of herpes simplex virus type 1 glycoprotein B. J Gen Virol 70 ( Pt 3):735-41

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