Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE008681-05
Application #
2130149
Study Section
Special Emphasis Panel (ZRG4-OBM-2 (06))
Project Start
1990-03-01
Project End
1998-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Loma Linda University
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Loma Linda
State
CA
Country
United States
Zip Code
92350

  Publications

Lau, K-H William; Baylink, David J (2003) Osteoblastic tartrate-resistant acid phosphatase: its potential role in the molecular mechanism of osteogenic action of fluoride. J Bone Miner Res 18:1897-900
Lau, K-H William; Goodwin, C; Arias, M et al. (2002) Bone cell mitogenic action of fluoroaluminate and aluminum fluoride but not that of sodium fluoride involves upregulation of the insulin-like growth factor system. Bone 30:705-11
Hashimoto, H; Lau, K H (2001) Differential effects of bacterial toxins on mitogenic actions of sodium fluoride and those of aluminum fluoride in human TE85 osteosarcoma cells. Mol Cell Biochem 228:91-8
Yoon, H K; Baylink, D J; Lau, K H (2000) Protein tyrosine kinase inhibitors block the stimulatory actions of phosphotyrosine phosphatase inhibitors to increase cell proliferation, alkaline phosphatase activity, and collagen synthesis in normal human bone cells. Am J Nephrol 20:153-62
Lau, K H; Baylink, D J (1999) Vitamin D therapy of osteoporosis: plain vitamin D therapy versus active vitamin D analog (D-hormone) therapy. Calcif Tissue Int 65:295-306
Lau, K H; Baylink, D J (1998) Molecular mechanism of action of fluoride on bone cells. J Bone Miner Res 13:1660-7
Yoon, H K; Chen, K; Baylink, D J et al. (1998) Differential effects of two protein tyrosine kinase inhibitors, tyrphostin and genistein, on human bone cell proliferation as compared with differentiation. Calcif Tissue Int 63:243-9
Yoo, A; Tanimoto, H; Akesson, K et al. (1998) Effects of calcium depletion and repletion on serum insulin-like growth factor I and binding protein levels in weanling rats. Bone 22:225-32
Dimai, H P; Porta, S; Wirnsberger, G et al. (1998) Daily oral magnesium supplementation suppresses bone turnover in young adult males. J Clin Endocrinol Metab 83:2742-8
Akesson, K; Lau, K H; Johnston, P et al. (1998) Effects of short-term calcium depletion and repletion on biochemical markers of bone turnover in young adult women. J Clin Endocrinol Metab 83:1921-7

Showing the most recent 10 out of 30 publications