Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Research Project (R01)
Project #
5R01DE010985-02
Application #
2132006
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1995-02-01
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Gu, Ying; Lee, Hsi-Ming; Golub, Lorne M et al. (2005) Inhibition of breast cancer cell extracellular matrix degradative activity by chemically modified tetracyclines. Ann Med 37:450-60
O'Riordan, Thomas G; Seischab, Lori B; Ying, Qi-Long et al. (2005) Antiprotease function of airway secretions in purulent tracheobronchitis. Chest 128:3167-76
Ying, Qi-Long; Simon, Sanford R (2002) Elastolysis by proteinase 3 and its inhibition by alpha(1)-proteinase inhibitor: a mechanism for the incomplete inhibition of ongoing elastolysis. Am J Respir Cell Mol Biol 26:356-61
Ying, Q L; Simon, S R (2001) Kinetics of the inhibition of proteinase 3 by elafin. Am J Respir Cell Mol Biol 24:83-89
Gu, Y; Lee, H M; Roemer, E J et al. (2001) Inhibition of tumor cell invasiveness by chemically modified tetracyclines. Curr Med Chem 8:261-70
Ying, Q L; Simon, S R (2000) DNA from bronchial secretions modulates elastase inhibition by alpha(1)-proteinase inhibitor and oxidized secretory leukoprotease inhibitor. Am J Respir Cell Mol Biol 23:506-13
Ying, Q L; Kemme, M; Saunders, D et al. (1997) Glycosaminoglycans regulate elastase inhibition by oxidized secretory leukoprotease inhibitor. Am J Physiol 272:L533-41
Lee, H M; Golub, L M; Chan, D et al. (1997) alpha 1-Proteinase inhibitor in gingival crevicular fluid of humans with adult periodontitis: serpinolytic inhibition by doxycycline. J Periodontal Res 32:9-19
Ying, Q L; Kemme, M; Simon, S R (1996) Alginate, the slime exopolysaccharide of Pseudomonas aeruginosa, binds human leukocyte elastase, retards inhibition by alpha 1-proteinase inhibitor, and accelerates inhibition by secretory leukoprotease inhibitor. Am J Respir Cell Mol Biol 15:283-91
Ying, Q L; Simon, S R (1995) Accelerated binding of secretory leukoprotease inhibitor to human leukocyte elastase mediated by single-stranded sites in DNA from tracheobronchial mucus. Am J Respir Cell Mol Biol 13:703-11